anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Antikörper

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Zusätzlich bieten wir Ihnen Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KLRC1 29683  
KLRC1 3821 P26715
KLRC1 16641  
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Top anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 134 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of KLRC1 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). KLRC1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, IF, WB Confocal immunofluorescent analysis of KLRC1 / CD159a Antibody (N-term) Cat.-No AP52396PU-N with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). Western blot analysis of KLRC1 / CD159a Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the KLRC1 antibody detected the KLRC1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Maus Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Anti-NKG2A Polyclonal Antibody, Unconjugated (ABIN739875) at 1:200 followed by conjugation to the secondary antibody 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Maus PE FACS Detection of NKG2A/CD159a in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. Detection of NKG2A/CD159a in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 3 bis 4 Tage
134,00 €
Details
Human Maus Allophycocyanin FACS Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody. Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody. 25 Tests Anmelden zum Anzeigen 3 bis 4 Tage
134,00 €
Details
Human Maus PerCP FACS Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a PerCP-conjugated Mono-clonal Antibody. Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a PerCP-conjugated Mono-clonal Antibody. 25 Tests Anmelden zum Anzeigen 3 bis 4 Tage
145,00 €
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-KLRC1 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: MCF7 Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Meerschweinchen Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Maus Unkonjugiert CyTOF, FACS   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
280,00 €
Details
Human Kaninchen Unkonjugiert IF, WB KLRC1 Antibody (N-term) (ABIN656501) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the KLRC1 antibody detected the KLRC1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details

KLRC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Antikörper

  1. Human Monoclonal KLRC1 Primary Antibody für FACS - ABIN4898769 : Kruse, Hamann, Monecke, Cyganek, Elsner, Hübscher, Walter, Streckfuss-Bömeke, Guan, Dressel: Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. in PLoS ONE 2015 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal KLRC1 Primary Antibody für FACS - ABIN4898770 : Roberti, Juliá, Rocca, Amat, Bravo, Loza, Coló, Loza, Fabiano, Maino, Podhorzer, Fainboim, Barrio, Mordoh, Levy: Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade. in European journal of immunology 2015 (PubMed)
    Show all 13 Pubmed References

  3. Human Monoclonal KLRC1 Primary Antibody für CyTOF, FACS - ABIN4900828 : Angelini, Zambello, Galandrini, Diamantini, Placido, Micucci, Poccia, Semenzato, Borsellino, Santoni, Battistini: NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease. in Journal of leukocyte biology 2011 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal KLRC1 Primary Antibody für CyTOF, FACS - ABIN4900827 : Brando, Mukhopadhyay, Kovacs, Medina, Patel, Catina, Campbell, Santoli: Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104. in Journal of leukocyte biology 2005 (PubMed)
    Show all 6 Pubmed References

  5. Human Monoclonal KLRC1 Primary Antibody für FACS - ABIN4898763 : Ballan, Vu, Long, Loo, Michaëlsson, Barbour, Lanier, Wiznia, Abadi, Fennelly, Rosenberg, Nixon et al.: Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with ... in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal KLRC1 Primary Antibody für FACS - ABIN4898762 : Gill, Peppa, Micco, Singh, Carey, Foster, Maini, Kennedy: Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo. in PLoS pathogens 2016 (PubMed)
    Show all 5 Pubmed References

  7. Mouse (Murine) Polyclonal KLRC1 Primary Antibody für IF (p), IHC (p) - ABIN739875 : Hall, Murphy, Quinlan, Hurley, Shanahan, Nally, Melgar: Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor. in Mucosal immunology 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal KLRC1 Primary Antibody für FACS - ABIN4898765 : Curriu, Carrillo, Massanella, Rigau, Alegre, Puig, Garcia-Quintana, Castro-Marrero, Negredo, Clotet, Cabrera, Blanco: Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome. in Journal of translational medicine 2013 (PubMed)

Weitere Antikörper gegen Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Interaktionspartner

Human Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Interaktionspartner

  1. These results indicate NKG2A inhibitory receptor may play a key role in transfusion-induced immunodepression of NK cells in patients with b-thalassemia major

  2. Collectively, these results provide evidence for the first time that CD94 (zeige KLRD1 Antikörper)/NKG2C (zeige KLRC2 Antikörper) is involved in chronic graft-versus-host disease prevention

  3. CD94 (zeige KLRD1 Antikörper) and NKG2A polymorphisms may contribute to genetic susceptibility to rheumatoid arthritis or affect the response to anti-TNF (zeige TNF Antikörper) therapy in patients of Caucasian origin.

  4. NK cell maturation to CD56(dim) subset associated with high levels of NCRs overrides the inhibitory effect of NKG2A and recovers impaired NK cell cytolytic potential after allogeneic hematopoietic stem cell transplantation.

  5. Coengagement of inhibitory receptors, either KIR2DL1 (zeige KIR2DL1 Antikörper) or CD94 (zeige KLRD1 Antikörper)-NKG2A, did not inhibit phosphorylation of Stat5 (zeige STAT5A Antikörper) but inhibited selectively phosphorylation of Akt (zeige AKT1 Antikörper) and S6 ribosomal protein (zeige RPS6 Antikörper).

  6. The presence of TIM3 (zeige HAVCR2 Antikörper)+and/or NKG2A+ T cells is associated with the absence of recurrences and a longer recurrence-free survival.

  7. Balance between activating NKG2D (zeige KLRK1 Antikörper), DNAM-1 (zeige CD226 Antikörper), NKp44 (zeige NCR2 Antikörper) and NKp46 (zeige NCR1 Antikörper) and inhibitory CD94 (zeige KLRD1 Antikörper)/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  8. Results suggested that the low expression level of CD94 (zeige KLRD1 Antikörper)/NKG2A upon gammadelta T cell activation might lead to the over-activation of gammadelta T cells in patients with SLE.

  9. The positive expression rate of NKG2D (zeige KLRK1 Antikörper) and NKG2A on NK cells and CD3 (zeige CD3 Antikörper)(+) T cells in ALL patients was no significantly different from that in AML (zeige RUNX1 Antikörper) patients.

  10. The level of NKG2A expression on resting CD8 (zeige CD8A Antikörper)-positive T cells inversely correlated with acquisition of regulatory function when activated.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Interaktionspartner

  1. Here, we provide a new anti-inflammation mechanism about ANXA1 (zeige ANXA1 Antikörper) secreted from injured IECs, where ANXA1 (zeige ANXA1 Antikörper) can stimulate the expression of NKG2A in NK cells that affect the recruitment and activity of neutrophils necessary for pathology of colitis.

  2. NKG2A optimizes CD8 (zeige CD8A Antikörper)(+) T cell responses during an acute poxvirus infection.

  3. Results demonstrate the immunoregulatory role of CD8 (zeige CD8A Antikörper)(+) NKG2A expression in virus infection, which negatively regulates T cell effector functions and contributes to protection of tissue integrity during virus clearance.

  4. role in NK cell-mediated protection from DSS (zeige PMP22 Antikörper)-induced colitis

  5. Endogenous NKG2A contributes to the rejection of cells lacking human HLA-Cw3.

  6. The complex interplay between various stimuli may account for the variable expression of CD94 (zeige KLRD1 Antikörper)/NKG2A during responses to different pathogens in vivo.

  7. expression of CD94 (zeige KLRD1 Antikörper) and its associated NKG2A, NKG2C (zeige KLRC2 Antikörper), and NKG2E (zeige KLRC3 Antikörper) subunits is dispensable for NK cell development, education, and many NK cell functions

  8. The NKG2A+KLRG1 (zeige KLRG1 Antikörper)+ positive phenotype correlates with protective efficacy during antigenic recall from a pool of CD8 (zeige CD8A Antikörper) T cells during persistent gamma-herpesvirus 68 infection.

  9. Data suggest that the liver environment regulates NK cell receptor expression and that IL-10 contributes to the regulation of liver NK cells, in part, by maintaining a greater percentage of the hyporesponsive NKG2A(+)Ly49(-) NK cells in the liver.

  10. Implications of CD94 (zeige KLRD1 Antikörper) deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation.

Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Antigen-Profil

Protein Überblick

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit KLRC1

  • killer cell lectin-like receptor subfamily C, member 1 (Klrc1) Antikörper
  • killer cell lectin-like receptor subfamily C, member 1 (KLRC1) Antikörper
  • killer cell lectin-like receptor subfamily C, member 3 (KLRC3) Antikörper
  • CD159a Antikörper
  • KLRC1 Antikörper
  • NKG2 Antikörper
  • NKG2-A Antikörper
  • NKG2A Antikörper
  • NKG2B Antikörper
  • rNKG2A Antikörper

Bezeichner auf Proteinebene für KLRC1

natural killer cell protein group 2-A (NKG2A) , CD159 antigen-like family member A , NK cell receptor A , NKG2-A/B-activating NK receptor , NKG2-A/NKG2-B type II integral membrane protein , killer cell lectin-like receptor subfamily C, member 1 , C-lectin type II protein , NKG2-1/B activating NK receptor , NKG2-A/B type II integral membrane protein , natural killer cell lectin , natural killer group protein 2

GENE ID SPEZIES
29683 Rattus norvegicus
450131 Pan troglodytes
514897 Bos taurus
611325 Canis lupus familiaris
100126720 Papio anubis
100144622 Sus scrofa
3821 Homo sapiens
16641 Mus musculus
574146 Macaca mulatta
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