anti-Junctional Adhesion Molecule 3 (JAM3) Antikörper

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Zusätzlich bieten wir Ihnen JAM3 Proteine (13) und JAM3 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
JAM3 83964 Q9D8B7
JAM3 83700 Q9BX67
JAM3 315509 Q68FQ2
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Top anti-JAM3 Antikörper auf antikoerper-online.de

Showing 10 out of 99 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-JAM3 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert CyTOF, FACS, Neut, SimWes, WB Cell Adhesion Mediated by JAM-C and Neutralization by Human JAM-C Antibody. Recombinant Human JAM-B/ VE-JAM Fc Chimera. The ND50 is typically 2-8 ug/mL. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$440.45
Details
Human Maus PE FACS Detection of JAM-C in CD41+ Human Platelets by Flow Cytometry. Human platelets were stained with anti-human CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human JAM-C PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$357.65
Details
Human Maus Allophycocyanin FACS Detection of JAM-C in CD41+ Human Platelets by Flow Cytometry. Human platelets were stained with anti-human CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human JAM-C APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged JAM3 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Ratte Unkonjugiert FACS, IF, IHC (fro) 1 mg Anmelden zum Anzeigen 3 bis 4 Tage
$700.12
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of lysates from human placenta, mouse brain and rat brain tissue (from left to right), using JAM3 Antibody (C-term) (ABIN1882171). AP20552b was diluted at 1:1000 at each lane. A goat anti-rabbit(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ratte Unkonjugiert IHC (fro), FACS, IF, IP 0.25 mg Anmelden zum Anzeigen 3 bis 4 Tage
$420.59
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

JAM3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-JAM3 Antikörper

  1. Human Polyclonal JAM3 Primary Antibody für WB - ABIN1882171 : Arrate, Rodriguez, Tran, Brock, Cunningham: Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal JAM3 Primary Antibody für FACS, IF - ABIN2475176 : Matsuo, Aoki, Kawagoe, Kogure: [Pathophysiology of cerebral ischemia]. in Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1992 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal JAM3 Primary Antibody für IHC (fro), FACS - ABIN2475170 : Aurrand-Lions, Duncan, Ballestrem, Imhof: JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal JAM3 Primary Antibody für FACS, IF - ABIN2475174 : Aurrand-Lions, Johnson-Leger, Wong, Du Pasquier, Imhof: Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. in Blood 2001 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal JAM3 Primary Antibody für CyTOF, FACS - ABIN4900201 : Ludwig, Hardt, Hatting, Bistrian, Diehl, Radeke, Podda, Schön, Kaufmann, Henschler, Pfeilschifter, Santoso, Boehncke: Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin. in Immunology 2009 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal JAM3 Primary Antibody für FACS - ABIN4897344 : Erpenbeck, Rubant, Hardt, Santoso, Boehncke, Schön, Ludwig: Constitutive and functionally relevant expression of JAM-C on platelets. in Thrombosis and haemostasis 2010 (PubMed)
    Show all 2 Pubmed References

  7. Cow (Bovine) Polyclonal JAM3 Primary Antibody für ELISA - ABIN4227855 : Ueki, Iwasawa, Ishikawa, Sawa: Expression of junctional adhesion molecules on the human lymphatic endothelium. in Microvascular research 2008 (PubMed)

  8. Mouse (Murine) Monoclonal JAM3 Primary Antibody für D, IA - ABIN2191807 : Johnson-Léger, Aurrand-Lions, Beltraminelli, Fasel, Imhof: Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. in Blood 2002 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal JAM3 Primary Antibody für ICC, IF - ABIN4327907 : Asplund, Gry Björklund, Sundquist, Strömberg, Edlund, Ostman, Nilsson, Pontén, Lundeberg: Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma. in The British journal of dermatology 2008 (PubMed)

Weitere Antikörper gegen JAM3 Interaktionspartner

Zebrafish Junctional Adhesion Molecule 3 (JAM3) Interaktionspartner

  1. interaction between Jamb (zeige JAM2 Antikörper) and Jamc expressed by neighbouring cells is essential for fusion. jamc is ectopically expressed in prdm1a (zeige PRDM1 Antikörper) mutant slow muscle precursors, which inappropriately fuse with other myocytes.

Mouse (Murine) Junctional Adhesion Molecule 3 (JAM3) Interaktionspartner

  1. JAM-B (zeige JAM2 Antikörper)/JAM-C mediated interaction between endothelial cells and stellate cells stabilizes vessel walls and may control the sinusoidal diameter.

  2. Study provides evidence that JAM-C downregulation may contribute to acute pancreatitis-associated lung injury via reverse transendothelial migration of neutrophils.

  3. Endothelial-specific deletion of JAM-C promoted endothelial cell sprouting, and consequently vessel normalisation and revascularisation of the hypoxic retina without altering pathologic neovascularisation.

  4. JAM-C blockade can finely-tune the innate cell migration and accelerate the consequent immune response to L. major without changing the type of the T helper cell response.

  5. Function of Jam-B (zeige JAM2 Antikörper)/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.

  6. These findings provide evidence for a role for endothelial cell JAM-C in tumor growth and aggressiveness as well as recruitment of pericytes to newly formed blood vessels in a model of ovarian cancer.

  7. JAM-C might be involved in the final steps of trafficking and transmigration of antigen-specific autoaggressive T-cells to the islets of Langerhans.

  8. study suggests that JAM-C(-/-) C57BL/6 mice model the important role for JAM-C in brain development and CSF (zeige CSF2 Antikörper) homeostasis as recently observed in humans with a loss-of-function mutation in JAM-C

  9. Data show that junctional adhesion molecule-B (JAM-B (zeige JAM2 Antikörper)) expressed by endothelial cells contributes to murine B16 melanoma cells metastasis through its interaction with junctional adhesion molecule-C (JAM-C) on tumor cells.

  10. Results indicate that in vivo JAM-C shows enrichment at the apical surface and therefore is asymmetrically distributed during cell divisions.

Human Junctional Adhesion Molecule 3 (JAM3) Interaktionspartner

  1. The role of JAM-C in the engraftment of human lymphoma B cells in mice was investigated. The binding of anti-JAM-C antibodies inhibited the phosphorylation of ERK1/2 (zeige MAPK1/3 Antikörper), without affecting other signaling pathways, identifying for the first time the intracellular MAPK (zeige MAPK1 Antikörper) cascade as the JAM-C-driven signaling pathway in JAM-C(+) B cells.

  2. blocking JAM-C can reduce the number of atherogenic monocytes/macrophages in plaques by emigration.

  3. Palmitoylation of JAM-C promotes its localization to tight junctions and inhibits transwell migration of A549 lung cancer cells.

  4. Study provides evidence that JAM-C downregulation may contribute to acute pancreatitis-associated lung injury via reverse transendothelial migration of neutrophils.

  5. Suggest JAM3-M4 methylation as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervix.

  6. JAM-C inactivation in endothelial cells resulted in increased spreading on fibronectin and enhanced sprouting in vitro in a manner dependent on beta1-integrin and on the activation of the small GTPase RAP1.

  7. Function of Jam-B (zeige JAM2 Antikörper)/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.

  8. indicate that JAM-C may be a therapeutic target for preventing and treating lymphatic metastases

  9. These findings provide evidence for a role for endothelial cell JAM-C in tumor growth and aggressiveness as well as recruitment of pericytes to newly formed blood vessels in a model of ovarian cancer.

  10. Our study confirms the importance of JAM3 as a component of the junctional complexes and its deficiency leading to a distinctive and catastrophic neonatal presentation of cataracts and hemorrhagic destruction of the brain.

JAM3 Antigen-Profil

Protein Überblick

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit JAM3

  • junctional adhesion molecule 3 (JAM3) Antikörper
  • junctional adhesion molecule 3b (jam3b) Antikörper
  • junctional adhesion molecule 3a (jam3a) Antikörper
  • junction adhesion molecule 3 (Jam3) Antikörper
  • junctional adhesion molecule 3 (Jam3) Antikörper
  • 1110002N23Rik Antikörper
  • JAM-2 Antikörper
  • JAM-3 Antikörper
  • JAM-C Antikörper
  • jam3 Antikörper
  • JAMC Antikörper
  • jamc.2 Antikörper
  • Jcam3 Antikörper
  • sr:nyz155 Antikörper
  • wu:fb30h11 Antikörper
  • wu:fc08c06 Antikörper
  • wu:fc13e04 Antikörper
  • wu:fc25g11 Antikörper

Bezeichner auf Proteinebene für JAM3

junctional adhesion molecule 3 , jamc , jamc.1 , si:ch211-277g22.3 , JAM-C-like protein , junction cell adhesion molecule 3 , junction cell adhesion molecule C , junctional adhesion molecule C , JAM-3 , JAM-C

GENE ID SPEZIES
419736 Gallus gallus
451678 Pan troglodytes
569217 Danio rerio
797651 Danio rerio
83964 Mus musculus
83700 Homo sapiens
489271 Canis lupus familiaris
513412 Bos taurus
315509 Rattus norvegicus
Ausgewählte Anbieter für anti-JAM3 (JAM3) Antikörper
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