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JAM3 Antikörper (Junctional Adhesion Molecule 3) Primary Antibody

JAM3 Reaktivität: Maus IA, IHC (fro), FACS, IP Wirt: Ratte Monoclonal CRAM-19 H36 unconjugated
Pubmed (1 reference)
Produktnummer ABIN2191806
$605.98
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle JAM3 Antikörper anzeigen
    JAM3
    Reaktivität
    • 58
    • 42
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 38
    • 14
    • 7
    • 3
    Ratte
    Klonalität
    • 45
    • 17
    Monoklonal
    Konjugat
    • 32
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JAM3 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 21
    • 14
    • 13
    • 13
    • 13
    • 12
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Sterilität
    0.2 μm filtered
    Klon
    CRAM-19 H36
  • Applikationshinweise
    For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Johnson-Léger, Aurrand-Lions, Beltraminelli, Fasel, Imhof: "Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration." in: Blood, Vol. 100, Issue 7, pp. 2479-86, (2002) (PubMed).

  • Target
    JAM3
    Andere Bezeichnung
    Junctional Adhesion Molecule-C (JAM3 Produkte)
    Synonyme
    JAM3, jam3, sr:nyz155, wu:fb30h11, wu:fc08c06, wu:fc13e04, wu:fc25g11, jamc.2, 1110002N23Rik, JAM-3, JAM-C, Jcam3, JAM-2, JAMC, junctional adhesion molecule 3, junctional adhesion molecule 3b, junctional adhesion molecule 3a, junction adhesion molecule 3, JAM3, jam3b, jam3a, Jam3
    Hintergrund
    Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. Monoclonal antibody CRAM-19 H36 also reacts with human JAM-C. In humans, JAM-C expression is not restricted to endothelial cells, but is also expressed on human lymphocytes.
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