Interleukin 31 Proteine (IL31)

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. Zusätzlich bieten wir Ihnen Interleukin 31 Antikörper (111) und Interleukin 31 Kits (52) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL31 386653 Q6EBC2
IL31 76399 Q6EAL8
IL31 690028  
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Showing 10 out of 41 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Maus Unkonjugiert 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
692,59 €
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HOST_Human Cells Human His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
200,00 €
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HOST_Human Cells Maus His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
523,81 €
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HOST_Escherichia coli (E. coli) Ratte His tag,GST tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
728,57 €
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HOST_Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
977,78 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
218,90 €
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HOST_Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
680,00 €
Details

IL31 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine) , ,
,
Rat (Rattus)

Weitere Proteine zu Interleukin 31 (IL31) Interaktionspartnern

Human Interleukin 31 (IL31) Interaktionspartner

  1. The first demonstration of the involvement of the IL-31/IL-31R axis in cancer came from studies in patients with mycosis fungoides/Sezary syndrome, the most frequent, cutaneous T cell lymphoma. Tumor cells were shown to produce IL-31, whose serum levels correlated with pruritus intensity.

  2. IL31 and its receptor, IL31RA (zeige IL31RA Proteine), are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.

  3. this study shows that IL-31 may be involved in the pathogenesis of asthma and rhinitis; dust mite and mugwort allergy could increase it significantly

  4. While serum TSLP (zeige TSLP Proteine) levels were unaffected by concomitant allergies and atopic comorbidities, serum levels of IL-31, IL-33 (zeige IL33 Proteine) and sST2 (zeige SSTR2 Proteine) were affected to a small extent. We found a positive correlation between TSLP (zeige TSLP Proteine), IL-31 and IL-33 (zeige IL33 Proteine), and an inverse relationship between IL-33 (zeige IL33 Proteine) and sST2 (zeige SSTR2 Proteine)

  5. Suggest that IL-31 gene may play a role in the development of systemic lupus erythematosus.

  6. High IL31 expression is associated with Endometrial Cancer.

  7. In a CML (zeige BCR Proteine) patient with pruritus receiving imatinib mesylate, IL-31 and IL-33 (zeige IL33 Proteine) serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33 (zeige IL33 Proteine), and the consequent interaction with its receptor on mast cells, inducing IL-31 secretion. The IL-31/IL-33 (zeige IL33 Proteine) axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.

  8. Distinct polymorphic variants of the IL-31 gene may be involved in the patho-genesis of mastocytosis, and IL-31 may be involved in the induction of pruritus in patients with mastocytosis.

  9. Serum/pleural fluid IL-31 levels are elevated in tuberculous pleural effusion.

  10. both SCF (zeige KITLG Proteine) and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma.

Mouse (Murine) Interleukin 31 (IL31) Interaktionspartner

  1. IL31 and its receptor, IL31RA (zeige IL31RA Proteine), are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.

  2. Oncostatin M (zeige OSM Proteine) and interleukin-31: Cytokines, receptors, signal transduction and physiology.

  3. IL-31 upregulates IL-31RA (zeige IL31RA Proteine) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (zeige IL31RA Proteine) expression in mice

  4. our results suggest a functional cooperation between NFAT1 (zeige NFAT1 Proteine) and JunB (zeige JUNB Proteine) in mediating IL-31 gene expression in CD4 (zeige CD4 Proteine)(+) T cells

  5. Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.

  6. IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases

  7. IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.

  8. these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.

Interleukin 31 (IL31) Protein Überblick

Protein Überblick

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004

Genbezeichner und Symbole assoziert mit Interleukin 31 Proteine (IL31)

  • interleukin 31 (IL31)
  • interleukin 31 (Il31)
  • 1700013B14Rik Protein
  • IL-31 Protein
  • IL31 Protein

Bezeichner auf Proteinebene für Interleukin 31 Proteine (IL31)

interleukin 31 , interleukin-31 , IL-31

GENE ID SPEZIES
701655 Macaca mulatta
744097 Pan troglodytes
100144624 Sus scrofa
386653 Homo sapiens
76399 Mus musculus
690028 Rattus norvegicus
100302725 Canis lupus familiaris
101903065 Bos taurus
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