anti-Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) Antikörper

The protein encoded by FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. Zusätzlich bieten wir Ihnen FXR1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FXR1 14359 Q61584
FXR1 8087 P51114
FXR1 361927 Q5XI81
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-FXR1 Antikörper auf antikoerper-online.de

Showing 10 out of 97 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FXR1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-FXR1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Maus Ziege Unkonjugiert ELISA, WB ABIN185683 (0.2µg/ml) staining of NIH/3T3 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$375.38
Details
Maus Kaninchen Unkonjugiert WB FXR1 Antibody (N-term) (ABIN1881357) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the FXR1 antibody detected the FXR1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: FXR1 Antibody [NBP1-89546] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunocytochemistry/Immunofluorescence: FXR1 Antibody [NBP1-89546] - Staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: FXR1 Antibody [NBP1-33719] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/Immunofluorescence: FXR1 Antibody [NBP1-33719] - Analysis of methanol-fixed HeLa, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Hund Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Maus Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

FXR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) , ,
, ,
,
, , , , , , , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , ,
Rat (Rattus) , ,
,

, , , , , , , , , , , , ,

Am meisten referenzierte anti-FXR1 Antikörper

  1. Mouse (Murine) Polyclonal FXR1 Primary Antibody für WB - ABIN1881357 : Coffee, Tessier, Woodruff, Broadie: Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. in Disease models & mechanisms 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal FXR1 Primary Antibody für ICC, IF - ABIN4312875 : Fischer-Kešo, Breuninger, Hofmann, Henn, Röhrig, Ströbel, Stoecklin, Hofmann: Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins. in Molecular and cellular biology 2014 (PubMed)

  3. Human Polyclonal FXR1 Primary Antibody für IF (p), IHC (p) - ABIN710891 : Zhao, Xu, Yuan, Jiang, Zhou, Li, Yin, Zhou, Zhang, Wang: 8-Methoxypsoralen disrupts MDR3-mediated phospholipids efflux and bile acid homeostasis and its relevance to hepatotoxicity. in Toxicology 2017 (PubMed)

Weitere Antikörper gegen FXR1 Interaktionspartner

Mouse (Murine) Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) Interaktionspartner

  1. FXR1P is a GSK3beta (zeige GSK3b Antikörper) substrate with a role in regulating mood and emotion processing

  2. Removal of FXR1P from the forebrain of postnatal mice selectively enhances long-term storage of spatial memories, hippocampal late-phase long-term potentiation (L-LTP (zeige SCP2 Antikörper)), and de novo GluA2 (zeige GRIA2 Antikörper) synthesis.

  3. FXR1P was highly expressed during hippocampal development and co-localized with ribosomes and mRNAs in the dendrite and at a subset of spines.

  4. FXR1P is required for efficient processing of pre-microR-9 and pre-microR-124 in vitro and forms a complex with Dicer (zeige DICER1 Antikörper) and pre-miRNAs.

  5. Fxr1 knockout hearts exhibit an up-regulation of desmoplakin (zeige DSP Antikörper) and talin2 proteins, which is accompanied by severe disruption of desmosome as well as costamere architecture and composition in the heart

  6. Targeting the p38 mitogen-activated protein kinase (zeige MAPK14 Antikörper) pathway of LPS (zeige TLR4 Antikörper)-treated cells with small molecule inhibitors can induce FXR1 protein expression.

  7. Four FXR1 isoforms of molecular weight 70, 74, 78, 80 kDa are widely distributed in mouse organs, while in striated (zeige NSDHL Antikörper) muscles these isoforms are replaced by proteins of 82 and 84 kDa containing an extra pocket of 27 amino acids.

  8. FXR1P operates as a repressor of TNF (zeige TNF Antikörper) translation

  9. the data clearly demonstrate the importance of FXR1P RBP (zeige RBP4 Antikörper) in the regulation of a wide spectrum of inflammatory genes and suggest an important role of MAP signalling in the response of macrophages to selected TLR ligands, including CpG.

  10. Fxr1 regulates mammalian circadian behavioral rhythms.

Xenopus laevis Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) Interaktionspartner

  1. Fxr1 plays a vital role during Xenopus embryogenesis. Knockdown of Fxr1 has highly muscle-specific (zeige EIF3K Antikörper) effects leading to disruption of MyoD (zeige MYOD1 Antikörper) expression, inhibition of somite myotomal cell rotation and segmentation, and abnormal dermatome formation.

Human Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) Interaktionspartner

  1. human microbiota was able to reduce the levels of tauro-beta-muricholic acid and induce expression of FXR (zeige NR1H4 Antikörper) target genes Fgf15 and Shp (zeige LAMC1 Antikörper) in ileum after long-term colonization. We show that a human microbiota can change BA composition and induce FXR (zeige NR1H4 Antikörper) signaling in colonized mice, but the levels of secondary BAs produced are lower than in mice colonized with a mouse microbiota

  2. These data reveal a new role of FXR1 in controlling induction of monocyte migration.

  3. FXR1 binds and destabilizes p21 (zeige CDKN1A Antikörper) mRNA, binds and stabilizes TERC RNA and suppresses the cellular senescence in oral cancer cells.

  4. FXR1P interacts with CMAS, and that FXR1P may enhance the activation of sialic acid via interaction with CMAS, and increase GM1 levels to affect the development of the nervous system, thus providing evidence for further research into the pathogenesis of FXS.

  5. P97 (zeige EIF4G2 Antikörper) interacts with 3' UTR (zeige UTS2R Antikörper)-binding FXR1a-associated microRNPs and with PARN (zeige PARN Antikörper), which binds mRNA 5' caps (zeige CAPS Antikörper), forming a specialized complex to translate recruited mRNAs in these altered canonical translation conditions.

  6. An accumulation of 8 SNPs in the fragile gene family (FMR1 (zeige FMR1 Antikörper), FXR1 and FXR2 (zeige FXR2 Antikörper))were found associated with autistic traits in a sample of male patients.

  7. FXR1P is a GSK3beta (zeige GSK3b Antikörper) substrate with a role in regulating mood and emotion processing

  8. The mechanisms by which FXR1 executes its regulatory function by forming a novel complex with two other oncogenes, protein kinase C (zeige PKC Antikörper), iota and epithelial cell transforming 2, located in the same amplicon via distinct binding mechanisms, were identified.

  9. binding of PKP1 (zeige PKP1 Antikörper)/3 to FXR1 was RNA independent, and both PKP3 (zeige PKP3 Antikörper) and FXR1 stabilized PKP2 (zeige PKP2 Antikörper) mRNA.

  10. Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A (zeige LMNA Antikörper) p.R482W mutation elicits a myogenic gene expression program in preadipocytes.

FXR1 Antigen-Profil

Protein Überblick

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit FXR1

  • FMR1 autosomal homolog 1 (fxr1) Antikörper
  • FMR1 autosomal homolog 1 (FXR1) Antikörper
  • fragile X mental retardation gene 1, autosomal homolog (Fxr1) Antikörper
  • FMR1 autosomal homolog 1 (Fxr1) Antikörper
  • FMR1 autosomal homolog 1 L homeolog (fxr1.L) Antikörper
  • fragile X mental retardation, autosomal homolog 1 (FXR1) Antikörper
  • fragile X mental retardation, autosomal homolog 1 (fxr1) Antikörper
  • 1110050J02Rik Antikörper
  • 9530073J07Rik Antikörper
  • AI851072 Antikörper
  • FXR1 Antikörper
  • Fxr1h Antikörper
  • FXR1P Antikörper
  • wu:fb16f11 Antikörper
  • wu:fd18c10 Antikörper
  • xfxr1 Antikörper
  • xFxr1p Antikörper
  • XtFxr1p Antikörper
  • zgc:66226 Antikörper

Bezeichner auf Proteinebene für FXR1

Fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 , fragile X mental retardation, autosomal homolog 1 , fragile X mental retardation-related protein 1 , fragile X mental retardation syndrome-related protein 1-like , fragile X mental retardation gene, autosomal homolog , fragile-X-related protein 1 , mFxr1p , fragile X-related protein , FXR1 , fragile X mental retardation syndrome-related protein 1 homolog A , xFxr1p-A , hFXR1p , fragile X mental retardation gene 1, autosomal homolog

GENE ID SPEZIES
594894 Xenopus (Silurana) tropicalis
710170 Macaca mulatta
746398 Pan troglodytes
100066076 Equus caballus
100172974 Pongo abelii
100340080 Oryctolagus cuniculus
100399500 Callithrix jacchus
100595780 Nomascus leucogenys
14359 Mus musculus
100689323 Cricetulus griseus
398050 Xenopus laevis
424968 Gallus gallus
8087 Homo sapiens
478642 Canis lupus familiaris
536793 Bos taurus
361927 Rattus norvegicus
100155866 Sus scrofa
327220 Danio rerio
Ausgewählte Anbieter für anti-FXR1 (FXR1) Antikörper
Haben Sie etwas anderes gesucht?