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FXR1 Antikörper (N-Term)

FXR1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB41819 unconjugated
Produktnummer ABIN1881357
  • Target Alle FXR1 Antikörper anzeigen
    FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
    Bindungsspezifität
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 37-66, N-Term
    Reaktivität
    • 40
    • 39
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 49
    • 3
    • 1
    Kaninchen
    Klonalität
    • 48
    • 5
    Polyklonal
    Konjugat
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FXR1 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 28
    • 10
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, Ha, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
    Klon
    RB41819
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FXR1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Coffee, Tessier, Woodruff, Broadie: "Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P." in: Disease models & mechanisms, Vol. 3, Issue 7-8, pp. 471-85, (2010) (PubMed).

    Darnell, Fraser, Mostovetsky, Darnell: "Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs." in: Human molecular genetics, Vol. 18, Issue 17, pp. 3164-77, (2009) (PubMed).

    Purcell, Wray, Stone, Visscher, ODonovan, Sullivan, Sklar: "Common polygenic variation contributes to risk of schizophrenia and bipolar disorder." in: Nature, Vol. 460, Issue 7256, pp. 748-52, (2009) (PubMed).

    Davidovic, Sacconi, Bechara, Delplace, Allegra, Desnuelle, Bardoni: "Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients." in: Journal of medical genetics, Vol. 45, Issue 10, pp. 679-85, (2008) (PubMed).

    Vasudevan, Steitz: "AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2." in: Cell, Vol. 128, Issue 6, pp. 1105-18, (2007) (PubMed).

  • Target
    FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
    Andere Bezeichnung
    FXR1 (FXR1 Produkte)
    Synonyme
    FXR1P antikoerper, wu:fb16f11 antikoerper, wu:fd18c10 antikoerper, zgc:66226 antikoerper, Fxr1h antikoerper, Fxr1p antikoerper, XtFxr1p antikoerper, fxr1h antikoerper, xFxr1p antikoerper, FXR1 antikoerper, 1110050J02Rik antikoerper, 9530073J07Rik antikoerper, AI851072 antikoerper, xfxr1 antikoerper, fxr1 antikoerper, FMR1 autosomal homolog 1 antikoerper, fragile X mental retardation, autosomal homolog 1 antikoerper, fragile X mental retardation gene 1, autosomal homolog antikoerper, FMR1 autosomal homolog 1 L homeolog antikoerper, FMR1 autosomal homolog 1 S homeolog antikoerper, FXR1 antikoerper, fxr1 antikoerper, Fxr1 antikoerper, fxr1.L antikoerper, fxr1.S antikoerper
    Hintergrund
    The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    69721
    NCBI Accession
    NP_001013456, NP_001013457, NP_005078
    UniProt
    P51114
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