anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Antikörper

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Zusätzlich bieten wir Ihnen DNA (Cytosine-5-)-Methyltransferase 3 Like Proteine (11) und DNA (Cytosine-5-)-Methyltransferase 3 Like Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRDMT1 445264  
TRDMT1 29947 Q9UJW3
TRDMT1 309680 Q1LZ50
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Top anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Antikörper auf antikoerper-online.de

Showing 10 out of 171 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Mouse Dnmt3L Antibody (ABIN387907) in Hela cell line lysates (35 µg/lane). Dnmt3l (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of DNMT3L Antibody (C-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the DNMT3L antibody detected the DNMT3L protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Dnmt3L-R322 (ABIN387892) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the DNMT3L antibody detected the DNMT3L protein (arrow). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert AA, ICC, IF, IHC, IP, WB SMC 341DNMT3LRat Tissue Mix Western Blotting. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
411,87 €
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Human Kaninchen Unkonjugiert EIA, IP, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
391,60 €
Details
Human Maus HRP AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
453,77 €
Details
Human Maus FITC AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
458,56 €
Details
Human Maus Alkaline Phosphatase (AP) AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,95 €
Details

TRDMT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Antikörper

  1. Human Monoclonal TRDMT1 Primary Antibody für AA, ICC - ABIN863134 : Bestor, Laudano, Mattaliano, Ingram: Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. in Journal of molecular biology 1989 (PubMed)
    Zeige alle 8 Referenzen für 863134

  2. Human Polyclonal TRDMT1 Primary Antibody für EIA, IHC (p) - ABIN356577 : Kierszenbaum: Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths. in Molecular reproduction and development 2002 (PubMed)
    Zeige alle 5 Referenzen für 356577

  3. Human Monoclonal TRDMT1 Primary Antibody für AA, ICC - ABIN2482691 : Xie, Wang, Okano, Nogami, Li, He, Okumura, Li: Cloning, expression and chromosome locations of the human DNMT3 gene family. in Gene 1999 (PubMed)
    Zeige alle 3 Referenzen für 2482691

  4. Human Monoclonal TRDMT1 Primary Antibody für AA, ICC - ABIN2482690 : Okano, Bell, Haber, Li: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. in Cell 1999 (PubMed)
    Zeige alle 3 Referenzen für 2482690

  5. Human Monoclonal TRDMT1 Primary Antibody für AA, ICC - ABIN2482687 : Reik, Kelsey, Walter: Dissecting de novo methylation. in Nature genetics 1999 (PubMed)
    Zeige alle 3 Referenzen für 2482687

  6. Human Polyclonal TRDMT1 Primary Antibody für IHC (p), WB - ABIN387892 : Chedin, Lieber, Hsieh: The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 3 Referenzen für 387892

  7. Human Polyclonal TRDMT1 Primary Antibody für EIA, WB - ABIN356591 : Okazaki, Furuno, Kasukawa, Adachi, Bono, Kondo, Nikaido, Osato, Saito, Suzuki, Yamanaka, Kiyosawa, Yagi, Tomaru, Hasegawa, Nogami, Schönbach, Gojobori, Baldarelli, Hill, Bult, Hume, Quackenbush et al.: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ... in Nature 2002 (PubMed)
    Zeige alle 3 Referenzen für 356591

  8. Human Polyclonal TRDMT1 Primary Antibody für WB - ABIN387907 : Bourchis, Xu, Lin, Bollman, Bestor: Dnmt3L and the establishment of maternal genomic imprints. in Science (New York, N.Y.) 2001 (PubMed)
    Zeige alle 2 Referenzen für 387907

  9. Human Polyclonal TRDMT1 Primary Antibody für EIA, WB - ABIN951958 : Manderwad, Gokul, Kannabiran, Honavar, Khosla, Vemuganti: Hypomethylation of the DNMT3L promoter in ocular surface squamous neoplasia. in Archives of pathology & laboratory medicine 2010 (PubMed)
    Zeige alle 2 Referenzen für 951958

Weitere Antikörper gegen DNA (Cytosine-5-)-Methyltransferase 3 Like Interaktionspartner

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Interaktionspartner

  1. The Dnmt3l mutation greatly reduced DNA methylation (zeige HELLS Antikörper) levels at most retrotransposons, but its impact on their RNA abundance was limited in prospermatogonia. In Pld6 (zeige PLD6 Antikörper) mutant germ cells, although only a few retrotransposons exhibited reduced DNA methylation (zeige HELLS Antikörper), many showed increased expression at the RNA level.

  2. Dnmt3l-KO donor cells may offer a more permissive epigenetic state that is beneficial for Nuclear transfer reprogramming

  3. By interacting with TRIM28 (zeige TRIM28 Antikörper), DNMT3L can attract various enzymes to form a DNMT3L-induced repressive complex to remove active marks and add repressive marks to histone proteins.

  4. Hypomethylation of highly methylated CpG islands was caused by the downregulation of Dnmt3L and Dnmt3a (zeige DNMT3A Antikörper) due to hepatitis B X-protein bound to their promoters.

  5. DNMT3L is required to delicately balance the cycling and quiescence of spermatogonial progenitor cells

  6. Study demonstrates that Dnmt3L interacts with the Polycomb (zeige CBX2 Antikörper) PRC2 complex in competition with the DNA methyltransferases Dnmt3a (zeige DNMT3A Antikörper) and Dnmt3b (zeige DNMT3B Antikörper) to maintain low methylation levels at the Histone 3 H3K27me3 regions.

  7. Data indicate that expression of Dnmt3a (zeige DNMT3A Antikörper), Dnmt3b (zeige DNMT3B Antikörper), Dnmt3L as well as maintenance Dnmt1o (zeige DNMT1 Antikörper) in oocytes and zygotes was not disrupted.

  8. Reduced expression of DNMT3L in male germ cells, associated with haploinsufficiency of the paternal-effect gene Dnmt3L, results in abnormal hypomethylation of prenatal germline progenitor cells.

  9. The maternal store of Dnmt3L is not involved in embryonic de novo methylation.

  10. Dnmt3l is one of the key players in de novo DNA methylation (zeige HELLS Antikörper) of imprinting control elements and retrotransposons, which occurs after genome-wide epigenetic erasure during germ cell development. (Review)

Human DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Interaktionspartner

  1. DNMT3L overexpression is associated with Down syndrome.

  2. the present study has demonstrated that variations in the DNMT3L gene do not contribute to stage I-II endometriosis-associated infertility.

  3. DNMT3L rs2070565 (genotype P = 0.007, allele P = 0.0026) confers an increased risk of developing schizophrenia at an early age in individuals with family history.

  4. crystal structures of DNMT3A (zeige DNMT3A Antikörper)-DNMT3L (autoinhibitory form) and DNMT3A (zeige DNMT3A Antikörper)-DNMT3L-H3 (active form) complexes at 3.82 and 2.90 A resolution, respectively

  5. DNMT3L can address DNMT3A (zeige DNMT3A Antikörper)/B to specific sites by directly interacting with TFs that do not directly interact with DNMT3A (zeige DNMT3A Antikörper)/B

  6. CpG island encompassing the promoter and first exon of human DNMT3L gene is a PcG/TrX (zeige VAC14 Antikörper) response element

  7. DNMT3L is one of the key players in de novo DNA methylation (zeige HELLS Antikörper) of imprinting control elements and retrotransposons, which occurs after genome-wide epigenetic erasure during germ cell development. (Review)

  8. SNP rs2070565, as well as haplotypes AAA (zeige APP Antikörper) and GAA (zeige GAA Antikörper), may be associated with male infertility; DNMT3L may contribute to azoospermia susceptibility in humans

  9. Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis.

  10. mutation analysis of SYCP3 (zeige SYCP3 Antikörper), DNMT3L and MSH4 (zeige MSH4 Antikörper) in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages.

DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Antigen-Profil

Protein Überblick

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TRDMT1

  • DNA methyltransferase 3-like, pseudogene 1 (Dnmt3l-ps1) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l) Antikörper
  • D6Ertd14e Antikörper
  • DNMT3L Antikörper
  • ecat7 Antikörper

Bezeichner auf Proteinebene für TRDMT1

DNA (cytosine-5-)-methyltransferase 3-like , cytosine-5-methyltransferase 3-like protein , DNA (cytosine-5)-methyltransferase 3-like , human cytosine-5-methyltransferase 3-like protein

GENE ID SPEZIES
445264 Mus musculus
470099 Pan troglodytes
608536 Canis lupus familiaris
613785 Bos taurus
100050680 Equus caballus
29947 Homo sapiens
54427 Mus musculus
309680 Rattus norvegicus
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