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anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antikörper

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Zusätzlich bieten wir Ihnen Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Kits (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CACNA1C 775 Q13936
CACNA1C 12288 Q01815
CACNA1C 24239 P22002
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Top anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Antikörper auf antikoerper-online.de

Showing 10 out of 167 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
REACT_Hamster Maus Unkonjugiert ICC, IF, IHC, IP, WB Cav1 2(S57-46) IP from INS-1E cells stained with anti-Cav1.2 poly Cav1.2 (S57-46), Mouse brain tissue, Amplifier 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
411,87 €
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of rat brain membranes: 1. Anti-CaV1.2 antibody, (1:200). 2. Anti-CaV1.2 antibody, preincubated with the control peptide antigen. Expression of Cav1.2 in mouse cerebellum Immunohistochemical staining of mouse cerebellum with Anti-Cav1.2 antibody. A. Cav1.2 (red) appears in Purkinje cells (horizontal arrows) and is distributed diffusely in the molecular layer (Mol) including in Purkinje dendrites (vertical arrows). B. Staining of Purkinje nerve cells with mouse anti-Calbindin 28K (green) demonstrates the location of dendrites in the molecular layer. C. Merged image of panels A and B. 50 μL Anmelden zum Anzeigen 6 bis 9 Tage
672,45 €
Details
Human Ziege Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
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Kaninchen Maus Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Ziege Unkonjugiert ELISA, WB EB08821 (0.5µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
341,55 €
Details
Maus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of Cav1.2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 7 bis 8 Tage
464,29 €
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Kaninchen Maus Unkonjugiert IHC, IP, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
440,00 €
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Human Kaninchen Unkonjugiert EIA, IP, WB   0.2 mL Anmelden zum Anzeigen 8 bis 10 Tage
440,00 €
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-CACNA1C / Cav1.2 antibody  ABIN1048367 IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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CACNA1C Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Am meisten referenzierte anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Antikörper

  1. Hamster Monoclonal CACNA1C Primary Antibody für ICC, IF - ABIN361759 : Krey, Moussay, Thiel, Ruemenapf: Role of the low-density lipoprotein receptor in entry of bovine viral diarrhea virus. in Journal of virology 2006 (PubMed)
    Zeige alle 3 Referenzen für ABIN361759

  2. Human Polyclonal CACNA1C Primary Antibody für EIA, IP - ABIN1105621 : Lemke, Welling, Christel, Blaich, Bernhard, Lenhardt, Hofmann, Moosmang: Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice. in The Journal of biological chemistry 2008 (PubMed)

  3. Human Polyclonal CACNA1C Primary Antibody für EIA, WB - ABIN375180 : Saud, Minobe, Wang, Han, Horiuchi, Hao, Kameyama: Calpastatin binds to a calmodulin-binding site of cardiac Cav1.2 Ca2+ channels. in Biochemical and biophysical research communications 2007 (PubMed)

  4. Human Polyclonal CACNA1C Primary Antibody für IHC, WB - ABIN1742110 : Kreuzberg, Theissen, Schicha, Schröder, Mehlhorn, de Vivie, Bokník, Neumann, Grohé, Herzig: Single-channel activity and expression of atrial L-type Ca(2+) channels in patients with latent hyperthyroidism. in American journal of physiology. Heart and circulatory physiology 2000 (PubMed)

Weitere Antikörper gegen Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Interaktionspartner

Xenopus laevis Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. Competitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2 (zeige CA2 Antikörper)+ channels by calmodulin (zeige Calm2 Antikörper) and Ca2 (zeige CA2 Antikörper)+-binding protein 1.

Rabbit Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. These findings suggest that N-glycosylation contributes to the surface expression and voltage-dependent gating of Cav1.2.

  2. Data show that cardiac L-type calcium (CaV1.2) channels form clusters that undergo dynamic, reciprocal, allosteric interactions.

  3. these findings provide evidence for a new role of Homer1 (zeige HOMER1 Antikörper) supporting the regulation of Cav1.2 channels by STIM1 (zeige STIM1 Antikörper).

  4. structural flexibility of CaV1.2 and CaV2.2 (zeige CACNA1B Antikörper) I-II proximal linker

  5. These results suggest a complex antagonistic interplay between G(q)-activated PKC and Gbetagamma in regulation of L-VDCC, in which multiple cytosolic segments of alpha(1C) are involved.

  6. There were substantial transmural gradients in Cav1.2, KChIP2 (zeige KCNIP2 Antikörper), ERG (zeige KCNH2 Antikörper), KvLQT1 (zeige KCNQ1 Antikörper), Kir2.1 (zeige KCNJ2 Antikörper), NCX1 (zeige SLC8A1 Antikörper), SERCA2a (zeige ATP2A2 Antikörper) and RyR2 (zeige RYR2 Antikörper) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  7. Ca v1.2 binding site for PP2A and PP2B

  8. Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 (zeige CACNA1E Antikörper) high-voltage gated calcium channels exchanges activation attributes.

  9. Coupled gating of Cav1.2 channels may represent a novel mechanism for the regulation of Ca(2 (zeige CA2 Antikörper)+) influx and excitability in neurons, cardiac, and arterial smooth muscle under physiological and pathological conditions.

  10. Sorcin (zeige SRI Antikörper) modulates cardiac L-type Ca2 (zeige CA2 Antikörper)+ current by functional interaction with the alpha1C subunit in rabbits.

Human Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. findings provide phenotypic detail of the CACNA1C AA genotype in non-symptomatic individuals, which suggest primary effects in emotional circuitry, consistent with previously documented alterations in hippocampal/amygdala processing.

  2. CACNA1C might play a role in the genetic etiology of autism in Chinese Han population.

  3. Study revealed no association between the 15 tagSNPs of CACNA1A (zeige CACNA1A Antikörper), 1C, and 1H and antiepileptic drug efficacy in the Chinese Han epileptic population; the TAGAA haplotype of CACNA1A (zeige CACNA1A Antikörper) may be a risk factor for drug resistance

  4. the consensus motifs of S-nitrosylation were much more abundant in Cav2.2 (zeige CACNA1B Antikörper) than in Cav1.2 and Cav2.1 (zeige CACNA1A Antikörper).

  5. This study showed that the risk rs1006737 genotype (AA) is correlated with increased levels of CACNA1C mRNA as compared with the non-risk or heterozygous (GG, GA) genotypes in induced human neuron.

  6. We identify novel CACNA1C missense mutation with mixed loss-of-function/gain-of-function responsible for a complex phenotype of LQTS, HCM, sudden cardiac death, and congenital heart defects.

  7. The CACNA1C gene was variably methylated in monozygotic twins discordant for depressive disorder.

  8. Findings support a role for the CACNA1C gene, particularly for the rs1006737, in schizophrenia.

  9. In overall, we provide evidence that Cav1.2 and Cav1.3 (zeige CACNA1D Antikörper) isoforms are capable of potentially functioning as zinc permeation routes, through which zinc entry can be differentially augmented by mild acidifications.

  10. the combined effects of the CACNA1C variant to diminish voltage-dependent inactivation of CaV1.2 and increase window current expand our appreciation of mechanisms by which a gain of function of CaV1.2 can contribute to QT prolongation

Mouse (Murine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. Both the extracellular PFXYD motif and the transmembrane domain of PLM (zeige FXYD1 Antikörper) but not the cytoplasmic tail were necessary for regulation of peak L-type Ca(2 (zeige CA2 Antikörper)+) current amplitude.

  2. Treatment of MSC (zeige MSC Antikörper) with BMP4 (zeige BMP4 Antikörper) caused a significant increase in expression of Cav1.2, a delay in expression of Cav1.1 (zeige CACNA1S Antikörper), and a reduction in the duration of calcium transients when extracellular calcium was removed

  3. data suggest that miR (zeige MLXIP Antikörper)-103 inhibits osteoblast proliferation mainly through suppression of Cav1.2 expression under simulated microgravity condition

  4. The down-regulation of Cav1.2 expression and the inhibition of LTCCs caused by mechanical unloading in osteoblasts are partially due to miR (zeige MLXIP Antikörper)-103 up-regulation.

  5. Ammonium-induced deregulation of astroglial Ca(2 (zeige CA2 Antikörper)+) signalling, is, in part, associated with upregulation of Cav1.2 L-type calcium channels

  6. Methamphetamine alters DNA methylation (zeige HELLS Antikörper), expression, and protein abundance of CACNA1C.

  7. demonstrate for the first time that both Cav1.2 and Cav1.3 (zeige CACNA1D Antikörper) are necessary for neuronal survival but are differentially required for the biophysical properties of neurons

  8. Our findings reveal that the intra-SR protein (zeige RNPS1 Antikörper) Casq2 (zeige CASQ2 Antikörper) is largely responsible for the phenomenon of SR Ca(2 (zeige CA2 Antikörper)+) release refractoriness in murine ventricular myocytes.

  9. results suggest the involvement of Cacna1c (Cav1.2) in fast electroencephalogram oscillations and REM (zeige REM1 Antikörper) sleep regulatory processes

  10. Cp8 is a new of Cav1.2 and Cav1.3 (zeige CACNA1D Antikörper) channel activators.

Cow (Bovine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. These results suggest that structural rearrangements of CaV1.2 generated through the binding of BayK8644 or FPL64176, by altering the channel activity, could affect depolarization-evoked catecholamine secretion prior to cation transport.

  2. CaV3.1 (zeige CACNA1G Antikörper) structural analysis and comparison to CaV1.2 channel

Guinea Pig Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Interaktionspartner

  1. These results suggest that PKA and phosphatase(s) attached on or near the Ca(V)1.2 channel regulate the basal channel activity, presumably through modulation of the dynamic CaM (zeige CALM Antikörper) interaction with the channel.

  2. CaM (zeige CALM Antikörper) may tether to the channel with its single lobe, leading to multiple CaM (zeige CALM Antikörper) molecule binding to increase the grade of Ca(2 (zeige CA2 Antikörper)+)-dependent regulation of Cav1.2

Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antigen-Profil

Protein Überblick

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Genbezeichner und Symbole assoziert mit CACNA1C

  • calcium channel, voltage-dependent, L type, alpha 1C subunit (cacna1c) Antikörper
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C) Antikörper
  • calcium channel (CACB) Antikörper
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (Cacna1c) Antikörper
  • cardiac L-type calcium channel (CACH2C) Antikörper
  • Red blood cell count (RBC) Antikörper
  • C-LTCC Antikörper
  • ca(v)1.2 Antikörper
  • CACH2 Antikörper
  • CACH2C Antikörper
  • CACN2 Antikörper
  • Cacna1c Antikörper
  • CACNL1A1 Antikörper
  • CAV1.2 Antikörper
  • Cchl1a1 Antikörper
  • CHCACHA1C Antikörper
  • ICA Antikörper
  • isl Antikörper
  • LQT8 Antikörper
  • MBC Antikörper
  • MELC-CC Antikörper
  • RATIVS302 Antikörper
  • TS Antikörper

Bezeichner auf Proteinebene für CACNA1C

ZfCav1.2 , island beat , voltage-dependent L-type calcium channel subunit alpha-1C , L-type Ca channel alpha 1 subunit , L-type calcium channel CaV1.2 , atrium L-type calcium channel , calcium channel, voltage-dependent, L type, alpha 1C subunit , voltage-dependent L-type calcium channel subunit alpha-1C-like , calcium channel voltage-dependent L type Cav1.2, alpha 1c subunit , CaCB receptor , smooth muscle calcium channel blocker , DHPR, alpha-1 subunit , calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle , calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit , voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* , L-type Cav1.2 , brain class C , calcium channel voltage-dependent alpha1c subunit , neuronal voltage-gated calcium channel alpha 1C subunit , skeletal muscle-specific calcium channel , voltage-gated calcium channel subunit alpha Cav1.2 , L-type calcium channel alpha-1 subunit , RBC , calcium channel, voltage-dependent, alpha 1C subunit , voltage-gated calcium channel alpha 1C subunit , L-type voltage-gated calcium channel alpha1C subunit ChCaChA1C , L-type voltage-dependent calcium channel alpha-1 subunit , cardiac L-type calcium channel , Voltage-dependent L-type calcium channel subunit alpha-1C

GENE ID SPEZIES
170581 Danio rerio
403516 Canis lupus familiaris
100442085 Pongo abelii
100462911 Xenopus laevis
100101555 Oryctolagus cuniculus
775 Homo sapiens
12288 Mus musculus
24239 Rattus norvegicus
408015 Bos taurus
395891 Gallus gallus
100135490 Cavia porcellus
100144322 Oryctolagus cuniculus
101180626 Sus scrofa
Ausgewählte Anbieter für anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antikörper
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