anti-C-Type Lectin Domain Family 5, Member A (CLEC5A) Antikörper

CLEC5A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen CLEC5A Proteine (10) und CLEC5A Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLEC5A 23601 Q9NY25
CLEC5A 23845 Q9R007
CLEC5A 679787  
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Top anti-CLEC5A Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 APC-conjugated Monoclonal Antibody. Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 APC-conjugated Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$278.25
Details
Maus Ratte Unkonjugiert CyTOF, FACS   500 μg Anmelden zum Anzeigen 8 bis 9 Tage
$351.75
Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti-CLEC5A/MDL1 Polyclonal Antibody (ABIN748763) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Ziege Unkonjugiert CyTOF, FACS, IHC, WB MDL-1/CLEC5A in Human Joint. MDL-1/CLEC5A was detected in formalin fixed paraffin-embedded sections of human rheumatoid arthritis joint using Goat Anti-Human MDL-1/CLEC5A Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to plasma membranes of monocyte colony cells in rheumatoid arthritis joint. Detection of Human MDL-1/CLEC5A by Western Blot. Western blot shows lysates of U937 human histiocytic lymphoma cell line. PVDF membrane was probed with 1 ug/mL of Goat Anti-Human MDL-1/CLEC5A Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$372.75
Details
Human Maus PE FACS Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 APC-conjugated Monoclonal Antibody. Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$315.00
Details
Human Maus Alexa Fluor 488 FACS Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$325.50
Details
Human Maus Alexa Fluor 700 FACS Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$325.50
Details
Human Maus Allophycocyanin FACS Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. Detection of MDL-1/CLEC5A in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with (A) Mouse Anti-Human Siglec-3/CD33 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$351.75
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details

CLEC5A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CLEC5A Antikörper

  1. Human Monoclonal CLEC5A Primary Antibody für CyTOF, FACS - ABIN4899948 : González-Domínguez, Domínguez-Soto, Nieto, Flores-Sevilla, Pacheco-Blanco, Campos-Peña, Meraz-Ríos, Vega, Corbí, Sánchez-Torres: Atypical Activin A and IL-10 Production Impairs Human CD16+ Monocyte Differentiation into Anti-Inflammatory Macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) Monoclonal CLEC5A Primary Antibody für CyTOF, FACS - ABIN4900815 : Charles, Hsu, Niemi, Weiss, Aliprantis, Nakamura: Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. in The Journal of clinical investigation 2012 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen CLEC5A Interaktionspartner

Human C-Type Lectin Domain Family 5, Member A (CLEC5A) Interaktionspartner

  1. Mannose Receptor and CLEC5A on Macrophage first attracts the Dengue Virus with high avidity, and the virus concurrently interacts with CLEC5A in close proximity to form a multivalent hetero-complex and facilitate CLEC5A-mediated signal transduction. Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex.

  2. The results suggest that CLEC5A-mediated enhancement of the inflammatory response in myeloid cells contributes to influenza pathogenicity in vivo and may be considered a therapeutic target in combination with effective antivirals.

  3. Concordant overexpression of MDL-1 and DAP12 (zeige TYROBP Antikörper) were correlated with increased production of proinflammatory cytokines in rheumatoid arthritis patients.

  4. Blockade of CLEC5A inhibits NLRP3 (zeige NLRP3 Antikörper) inflammasome activation and pyrotopsis in dengue-virus-infected inflammatory macrophages. Thus, DV can activate NLRP3 (zeige NLRP3 Antikörper) inflammasome via CLEC5A.

  5. No significant associations were noted between the genotypes and allele frequency of the 4 CLEC5A tSNPs between controls and Kawasaki disease patients.

  6. CLEC5A is homodimeric at the cell surface and binds to dengue virus serotypes 1-4.

  7. CLEC5A expression in monocyte/macrophage and granulocytes is regulated by PU.1.

  8. The crystal volume per unit weight (VM) was calculated to be 2.34 A3 Da-1 (zeige TPM2 Antikörper), with nine molecules per asymmetric unit and a solvent content of 47.38%. CLEC5A plays an important role in the pathophysiology of dengue-virus-induced disease.

  9. blockade of CLEC5A-mediated signalling attenuates the production of proinflammatory cytokines by macrophages infected with Dengue virus (either alone or complexed with an enhancing antibody)

Mouse (Murine) C-Type Lectin Domain Family 5, Member A (CLEC5A) Interaktionspartner

  1. The results suggest that CLEC5A-mediated enhancement of the inflammatory response in myeloid cells contributes to influenza pathogenicity in vivo and may be considered a therapeutic target in combination with effective antivirals.

  2. cigarette smoke-induced macrophage responsiveness is mediated by CLEC5A, and CLEC5A is required for the development of inflammation, proinflammatory cytokine expression, and airspace enlargement.

  3. Japanese encephalitis virus (JEV) directly interacts with CLEC5A and induces DAP12 (zeige TYROBP Antikörper) phosphorylation in macrophages.

  4. triggering of MDL-1 on immature myeloid cells and production of NO and TNF-alpha (zeige TNF Antikörper) may play a critical role in the pathogenesis of shock

  5. This is the first report that shows the involvement of monocyte and macrophage receptor CLEC5A in severe inflammatory response in Japanese encephalitis virus (JEV) infection of brain.

  6. Activation of MDL-1 leads to enhanced recruitment of inflammatory macrophages and neutrophils to the joint and promotes bone erosion.

  7. MDL-1 plays an important role in immune defense as a result of an innate immunity, which involves neutrophils and macrophages

  8. MDL-1 associates with both DAP12 (zeige TYROBP Antikörper) and DAP10 (zeige HCST Antikörper) in osteoclasts and bone marrow-derived macrophages, where DAP10 (zeige HCST Antikörper) association depends almost entirely on DAP12 (zeige TYROBP Antikörper), suggesting a formation of MDL-1-DAP12 (zeige TYROBP Antikörper)/DAP10 (zeige HCST Antikörper) trimolecular complexes.

CLEC5A Antigen-Profil

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.

Genbezeichner und Symbole assoziert mit CLEC5A

  • C-type lectin domain family 5, member A (CLEC5A) Antikörper
  • C-type lectin domain family 5, member a (Clec5a) Antikörper
  • C-type lectin domain family 5, member A (Clec5a) Antikörper
  • Clecsf5 Antikörper
  • Ly100 Antikörper
  • MDL-1 Antikörper
  • Mdl1 Antikörper

Bezeichner auf Proteinebene für CLEC5A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 , C-type lectin domain family 5 member A , C-type lectin superfamily member 5 , myeloid DAP12-associating lectin 1 , myeloid DAP12-associating lectin-1 , MDL-1 , myeloid DAP12-associating lectin long form , type II transmembrane protein MDL-1

GENE ID SPEZIES
23601 Homo sapiens
397050 Sus scrofa
615201 Bos taurus
23845 Mus musculus
679787 Rattus norvegicus
Ausgewählte Anbieter für anti-CLEC5A (CLEC5A) Antikörper
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