anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) Antikörper

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activa. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 1, Member B Proteine (10) und C-Type Lectin Domain Family 1, Member B Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLEC1B 500336  
CLEC1B 51266 Q9P126
CLEC1B 56760 Q9JL99
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Top anti-C-Type Lectin Domain Family 1, Member B Antikörper auf antikoerper-online.de

Showing 10 out of 124 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: CLEC1B Antibody [ABIN4087148] - (1ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert IP, ELISA, WB Detection limit for recombinant GST tagged CLEC1B is 1 ng/ml as a capture antibody. Immunoprecipitation of CLEC1B transfected lysate using anti-CLEC1B monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CLEC1B MaxPab rabbit polyclonal antibody. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CLEC2/CLEC1B Polyclonal Antibody, Unconjugated (ABIN741810) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Maus Ratte PE ICFC 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
284,71 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN263214 (1µg/ml) staining of human kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Maus Ratte PE FACS 100 Tests Anmelden zum Anzeigen 4 bis 5 Tage
427,06 €
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Human Maus Allophycocyanin FACS Detection of CLEC-2 in Human Whole Blood by Flow Cytometry. Human whole blood was stained with Mouse Anti-Human CD41 FITC-conjugated Monoclonal Antibody and either (A) Mouse Anti-Human CLEC-2 APC-conjugated Monoclonal Antibody. Detection of CLEC-2 in Human Whole Blood by Flow Cytometry. Human whole blood was stained with Mouse Anti-Human CD41 FITC-conjugated Monoclonal Antibody and either (A) Mouse Anti-Human CLEC-2 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 3 bis 4 Tage
330,00 €
Details

CLEC1B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-C-Type Lectin Domain Family 1, Member B Antikörper

  1. Mouse (Murine) Monoclonal CLEC1B Primary Antibody für ICFC - ABIN2662694 : Acton, Astarita, Malhotra, Lukacs-Kornek, Franz, Hess, Jakus, Kuligowski, Fletcher, Elpek, Bellemare-Pelletier, Sceats, Reynoso, Gonzalez, Graham, Chang, Peters, Woodruff, Kim, Swat, Morita, Kuchroo et al.: Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. ... in Immunity 2012 (PubMed)
    Zeige alle 6 Referenzen für 2662694

  2. Mouse (Murine) Monoclonal CLEC1B Primary Antibody für FACS - ABIN2473005 : de Lacey, McCabe, Constant, Welch, Spinks, McNally: Testing a policy for skull radiography (and admission) following mild head injury. in The British journal of radiology 1990 (PubMed)
    Zeige alle 3 Referenzen für 2473005

  3. Human Polyclonal CLEC1B Primary Antibody für ELISA, WB - ABIN408714 : Suzuki-Inoue, Kato, Inoue, Kaneko, Mishima, Yatomi, Yamazaki, Narimatsu, Ozaki: Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells. in The Journal of biological chemistry 2007 (PubMed)

  4. Human Monoclonal CLEC1B Primary Antibody für IP, ELISA - ABIN526588 : Manne, Badolia, Dangelmaier, Kunapuli: C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets. in Biochemical pharmacology 2015 (PubMed)

Weitere Antikörper gegen C-Type Lectin Domain Family 1, Member B Interaktionspartner

Human C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. NZ-1 inhibits the hPDPN-CLEC-2 interaction and is also useful for anti-PA tag MAb.The minimum epitope of LpMab-13 was identified as Ala42-Asp49 of hPDPN using Western blot and flow cytometry. The combination of different epitope-possessing MAbs could be advantageous for the hPDPN-targeting diagnosis and therapy

  2. CLEC2 prevents expression of PI3K (zeige PIK3CA Antikörper) subunits, in a SYK (zeige SYK Antikörper)-dependent manner, to suppress the invasive activities of gastric cancer cells.

  3. CLEC-2 regulates Akt and MAPK downstream of PI3K and PKC, leading to phosphorylation and inhibition of GSK3alpha/beta, and enhanced platelet aggregation and secretion.

  4. Data (including data from studies using recombinant proteins) suggest that a diverse range of ligands activate platelets through activation/phosphorylation (zeige CD36 Antikörper) of C (zeige GP6 Antikörper)D36/GPVI (glycoprotein VI) and/or CLEC-2 (C-type lectin-like receptor-2).

  5. PI3K (zeige PIK3CA Antikörper) and Tec (zeige NR4A3 Antikörper) family kinases play a crucial role in the regulation of platelet activation and Syk (zeige SYK Antikörper) phosphorylation downstream of the CLEC-2 receptor

  6. fucoidan is a novel CLEC-2 receptor agonist that activates platelets through a SFK-dependent signaling pathway

  7. Dimerization of two phosphorylated CLEC-2 molecules leads to recruitment of the tyrosine kinase Syk via its tandem SH2 domains and initiation of a downstream signaling cascade

  8. A differential proteomic analysis of basal and rhodocytin-activated platelets with the aim of providing novel clues on CLEC-2 signaling regulation.

  9. The glycosylation sites (N120 and N134) are necessary for the surface expression of CLEC-2.

  10. Shedding of CLEC-2 from the cell surface may reflect increased expression of this membrane protein and serve as a marker of disease activity.

Mouse (Murine) C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. a novel mechanism of Deep vein thrombosis, whereby CLEC-2 and upregulation of podoplanin (zeige PDPN Antikörper) expression in the venous wall trigger thrombus formation

  2. A reciprocal interaction between CLEC-2 on megakaryocytes and PDPN (zeige PDPN Antikörper) on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  3. A role for CLEC2 as a regulator of macrophage polarity and Kupffer cell polarity, lipid and glucose homeostasis

  4. Data indicate that C-type lectin-like receptor-2 (CLEC-2) is highly expressed on bone marrow megakaryocytes (Mks (zeige MKKS Antikörper)).

  5. Data (including data from studies in transgenic mice) suggest that a diverse range of ligands activate platelets through activation/phosphorylation of Cd36 (zeige CD36 Antikörper)/GPVI (zeige GP6 Antikörper) (glycoprotein VI) and/or Clec-2 (C-type lectin-like receptor-2).

  6. Podoplanin (zeige PDPN Antikörper) and CLEC-2 critically drive the formation and integrity of developing cerebral blood vessels.

  7. PI3K and Tec (zeige NR4A3 Antikörper) family kinases play a crucial role in the regulation of platelet activation and Syk (zeige SYK Antikörper) phosphorylation downstream of the CLEC-2 receptor

  8. CLEC-2 signaling promotes adhesion to Podoplanin (zeige PDPN Antikörper) and regulation of Podoplanin (zeige PDPN Antikörper) signaling, thereby contributing to lymphatic vasculature development.

  9. Under resting conditions, when FRCs are unlikely to encounter mature DCs expressing the PDPN (zeige PDPN Antikörper) receptor CLEC-2, PDPN (zeige PDPN Antikörper) endowed FRCs with contractile function and exerted tension within the reticulum.

  10. Functional studies of platelets from Ceacam2 (zeige CEACAM2 Antikörper)(-/-)-deficient mice (Cc2 (zeige TSG101 Antikörper)(-/-)) revealed that CEACAM2 (zeige CEACAM2 Antikörper) serves to negatively regulate collagen glycoprotein VI (platelet) (GPVI (zeige GP6 Antikörper))-FcRgamma (zeige FCER1G Antikörper)-chain and the C-type lectinlike receptor 2 (CLEC-2) signaling

C-Type Lectin Domain Family 1, Member B (CLEC1B) Antigen-Profil

Protein Überblick

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1\; MIM 602894) and NKG2D (KLRC4\; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000

Genbezeichner und Symbole assoziert mit CLEC1B

  • C-type lectin domain family 1, member B (CLEC1B) Antikörper
  • C-type lectin domain family 1, member B (Clec1b) Antikörper
  • C-type lectin domain family 1, member B (LOC100346882) Antikörper
  • C-type lectin domain family 1, member b (Clec1b) Antikörper
  • 1810061I13Rik Antikörper
  • Clec-2 Antikörper
  • CLEC1B Antikörper
  • Clec2 Antikörper
  • CLEC2B Antikörper
  • PRO1384 Antikörper
  • QDED721 Antikörper
  • RGD1563517 Antikörper

Bezeichner auf Proteinebene für CLEC1B

C-type lectin domain family 1, member B , C-type lectin domain family 1 member B , c-type lectin domain family 1 member B-like , C-type lectin-like receptor 2 , C-type lectin-like receptor-2 , CLEC-2

GENE ID SPEZIES
465283 Pan troglodytes
486696 Canis lupus familiaris
500336 Rattus norvegicus
717404 Macaca mulatta
784092 Bos taurus
100346882 Oryctolagus cuniculus
51266 Homo sapiens
56760 Mus musculus
Ausgewählte Anbieter für anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) Antikörper
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