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anti-Mouse (Murine) CD14 Antikörper:
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Mouse (Murine) Monoclonal CD14 Primary Antibody für FACS, WB - ABIN967379
Fearns, Kravchenko, Ulevitch, Loskutoff: Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide. in The Journal of experimental medicine 1995
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Human Monoclonal CD14 Primary Antibody für CyTOF, FACS - ABIN4899504
Zhang, Vernooij, Ibrahim, Ooi, Gijsberts, Schoneveld, Sen, den Ruijter, Timmers, Richards, Jong, Mazlan, Wang, Lam, de Kleijn: Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort. in PLoS ONE 2016
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Human Monoclonal CD14 Primary Antibody für ELISA, FACS - ABIN93966
Miko?ajczyk, Skrzeczy?ska-Moncznik, Zarebski, Marewicz, Wi?niewska, Dzieba, Dobrucki, Pryjma: Interaction of human peripheral blood monocytes with apoptotic polymorphonuclear cells. in Immunology 2009
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Human Monoclonal CD14 Primary Antibody für Func, FACS - ABIN93967
Kuronuma, Mitsuzawa, Takeda, Nishitani, Chan, Kuroki, Nakamura, Voelker: Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2. in The Journal of biological chemistry 2009
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Human Monoclonal CD14 Primary Antibody für ELISA, FACS - ABIN93965
Svensson: Isolation and culture of human hematopoietic progenitors for studies of dendritic cell biology. in Methods in molecular biology (Clifton, N.J.) 2009
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Mouse (Murine) Monoclonal CD14 Primary Antibody für BR, FACS - ABIN1176993
Nagaoka, Hirota, Niyonsaba, Hirata, Adachi, Tamura, Heumann: Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Human Monoclonal CD14 Primary Antibody für ELISA, FACS - ABIN192089
Weiss, Lichtenauer, Kirchner, Stock, Aurich, Christ, Brockhoff, Kunz-Schughart, Jauch, Schlitt, Thasler: Hepatic progenitor cells from adult human livers for cell transplantation. in Gut 2008
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Human Monoclonal CD14 Primary Antibody für Func, FACS - ABIN638430
Bazil, Baudys, Hilgert, Stefanová, Low, Zbrozek, Horejsí: Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD14. in Molecular immunology 1989
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Human Monoclonal CD14 Primary Antibody für Func, FACS - ABIN93963
Jursik, Prchal, Grillari-Voglauer, Drbal, Fuertbauer, Jungfer, Albert, Steinhuber, Hemetsberger, Grillari, Stockinger, Katinger: Large-scale production and characterization of novel CD4+ cytotoxic T cells with broad tumor specificity for immunotherapy. in Molecular cancer research : MCR 2009
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Human Monoclonal CD14 Primary Antibody für FACS - ABIN238455
Angel, Lala, Chen, Edgar, Ostrovsky, Dunbar: CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts. in International immunology 2007
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Overall, CD14/TLR4 signalling seems to be critical for intestinal barrier function and for the crosstalk between B cells and the epithelium, underlining that CD14 serves as a protective modulator of intestinal homeostasis.
Investigations on the variant of CD14 gene revealed negative association among ischemic stroke patients; however, a significant association was observed for hemorrhagic stroke following dominant and recessive genotypic model.
this paper shows that CD14 gene silencing alters the microRNA expression profile of RAW264.7 cells stimulated by Brucella melitensis infection
Data show that multiple phagocytes are capable of hyperactivation in response to oxPAPC, with CD14 antigen acting as the earliest regulator in this process, serving to capture and transport these lipids to promote inflammatory cell fate decisions.
Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1, Cd14, and Scara1 mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 and Scara1 in macrophages. (Lpar1 = LPA receptor 1; Cd14 = monocyte differentiation antigen CD14; Scara1 = scavenger receptor class A type I)
Stimulation of murine peritoneal macrophages with LPS induces biphasic accumulation of PI(4,5)P2 with peaks at 10 and 60-90 min that was abrogated when CD14 was removed from the cell surface.
these results indicate that CD14 is a co-receptor of TLR4 in the S100A9-induced cytokine response.
this study shows that lipid rafts may serve as sites in which LPS receptors (CD14) are sorted for endocytosis, rather than being platforms for the assembly of TLR4-centered signaling complexes
These findings suggested that the degree of lung injury was reduced during the acute inflammatory reaction when NFkappaB was inhibited, and that the expression of sphingomyelin synthase 2 may affect the induction of the NFkappaB pathway by lipopolysaccharide through CD14.
Results demonstrate remarkable sophistication of microglial CD14 in enabling, facilitating and moderating innate immune responses to infectious and non-infectious CNS threats of diverse kinds
CD14-mediated lipid signaling induced epithelial apoptosis, whereas TLR4 antagonistically promoted cell survival and cancer development.
fucosyllactose directly inhibits lipopolysaccharide-mediated inflammation during E. coli infection of intestinal epithelial cells through attenuation of CD14 induction.
studies revealed a novel physical association between SP-R210S, CD14, and SR-A leading to an enhanced response to LPS, and found that SP-R210L and SP-R210S regulate internalization of CD14 via distinct macropinocytosis-like mechanisms
Data indicate that Toll-like receptor 4 (TLR4) endocytosis and the TIR-domain-containing adapter-inducing IFN-beta (TRIF)-signaling pathway in macrophages during endotoxin tolerance in the absence of cluster of differentiation 14 (CD14).
27OHChol can prime monocytes/macrophages by up-regulation of CD14 such that LPS-mediated inflammatory reaction is accelerated, thereby contributing to aggravated development of atherosclerotic lesions.
microglial HSPGs facilitate CD14-dependent TLR4 activation and that heparanase can modulate this mechanism
Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.
In acute lung injury, lipopolysaccharide induced alveolar macrophage necrosis via CD14 and the P2X7 receptor leading to interleukin-1alpha release.
We demonstrated that TLR2, TLR4 and CD14 receptors sense Tityus serrulatus venom (TsV) and its major component, toxin 1 (Ts1), to mediate cytokine and lipid mediator production.
Gene expression of the anti-inflammatory cytokine IL-13 in prion-infected CD14(-/-) mice was temporarily upregulated at 75dpi, whereas IL-13 gene expression was not upregulated in prion-infected WT mice.
A high frequency of CCL2 positive breast tumor cells and CD14 positive tumor associated macrophages are significant risk factors for rapid tumor recurrence.
High presepsin expression is associated with hemophagocytic syndrome.
high plasma levels of sCD14 is associated with measles virus infection.
a considerable connection of DEFB1 and TCF7L2 gene polymorphisms with nephrolithiasis
CD14 C-(260)T polymorphism is not associated with incidence of acute myocardial infarction in Egyptians who showed elevated serum CD14 levels in
This study provides better understanding of the mechanisms and disease susceptibility for MIF and CD14 genetic variants and inflammatory miRNAs networks involved in ankylosing spondylitis and polyarthralgia.
Childhood-onset and adult-onset of asthma showed significant difference in allergen sensitivity as well as genetic background with respect to CD14 polymorphism.
Renal transplant recipients carrying the CD14-159 TT genotype have significantly higher risk of acute rejection and reduced transplant survival rate than patients with heterozygous or wild-type genotypes.
The accumulating evidence does not support an association of CD14 SNP rs2569190 with AR risk. [meta-analysis]
It seems that CD14 gene polymorphism might be associated with the risk of CAD, whereas COL4A1 gene polymorphism was not found to confer any risk of CAD
higher sCD14 levels in HIV-positive women were associated with a more compromised maternal immunological status and to a lower neonatal birthweight, but not to poorer clinical outcomes in the HIV-exposed children
The -221G>C polymorphism of MBL2, the -159C>T polymorphism of CD14 and the TNF-857 polymorphism of TNF-a are risk factors for spinal spinal tuberculosis (TB) and may be involved in the development of spinal TB in the Chinese population. These factors are indicators of susceptibility to spinal TB and require clinical attention.
genetic variation of CD14, rs5744455, is related to the susceptibility to laryngeal cancer, providing a theoretical basis for the study of the pathogenesis of laryngeal
Calcitriol regulates immune genes CD14 and CD180 to modulate LPS responses in human trophoblasts.
The findings suggest that smoking and the presence of TNFalpha-308 GA/AA genotypes may increase the risk for peri-implantitis, while CD14-159 polymorphic CT/TT genotypes decrease the risk.
Our results demonstrate that the expression of CD163 and CD206 in monocytes is modulated by LPS in vitro; LPS induces CD163 expression and downregulates the spontaneously increased expression of CD206
may be a simple and easy approach to assess by RT-FCM the reaction between NO and superoxide ion in whole blood monocytes..The no-wash, no-lyse staining protocol with CD45-KO and CD14-PB allows to differentiate clearly and to gate in the monocyte population in near-physiological conditions
Association of polymorphic markers of chemokine genes, their receptors, and CD14 gene with coronary atherosclerosis
data confirm that engineered human cells expressing TLR4, MD2 and CD14 can respond to CMP with NF-kappaB activation and the response can be influenced by variations in CMP-mannosylation
hypothesize that CD14(-159C/T) polymorphic variants might be one of genetic components in the response to attenuated M. bovis BCG bacilli
the CD14 single nucleotide polymorphisms identified in the present study, may be closely associated with the morbidity of mastitis.
results suggest that -5C/T and 613G/A single-nucleotide polymorphisms are risk factors for bovine tuberculosis in Chinese Holstein cattle
Transcription levels of TLR2, TLR4, and CD14 in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
Data from an in vitro co-culture model suggest that an early response of endometrium in uterine infection is up-regulation of expression of CD14 and TLR4 (toll-like receptor 4).
This study study confirmed that expression of CD14 in blood polymorpnuclear cells (PMN), resident PMN and inflammatory PMN from heifer mammary glands was accompanied by apoptosis and necrosis.
data are consistent with a role for lipopolysaccharide binding protein and soluble CD14 antigen molecules in mediating mammary gland responses to lipopolysaccharide(lipopolysaccharide binding protein- LBP)
Toll-like receptor 4 mRNA and CD14 mRNA and protein were detected in bovine endometrial stromal and epithelial cells by RT-PCR and flow cytometry.
First report of a functionally active animal receptor protein made in plants and the prophylactic use of a plant-derived protein to reduce the severity of bacterial infections in animals.
SNP and association analyses have provided baseline information that may be used at defining the role of CD14 in mediating bacterial infections
VB-201 may counter inflammation where TLR-2 and/or CD14 complicity is essential, and is therefore beneficial for the treatment of atherosclerosis.
Determine native soluble CD14 concentrations in serum from healthy and septic foals, in the colostrum of healthy mares and in plasma from adult horses with recurrent airway obstruction and control horses.
CD14 mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein.
monocyte differentiation antigen CD14
, myeloid cell-specific leucine-rich glycoprotein
, CD14 antigen
, lipopolysaccharide receptor