Der Kaninchen Polyklonal anti-CD14 Antikörper (ABIN3030357) detektiert spezifisch CD14 in FACS, WB, IHC und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
CD14
Reaktivität: Human
WB, IHC
Wirt: Maus
Monoclonal
LPSR-2397
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting amounts. Titration of the CD14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4oC for up to one month. For long term, aliquot the CD14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
CD14
Andere Bezeichnung
CD14
Hintergrund
In concert with LBP, CD14 binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. [UniProt]