IL-1 beta Protein
Kurzübersicht für IL-1 beta Protein (ABIN935526)
Target
Alle IL-1 beta (IL1B) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS
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Produktmerkmale
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Purified recombinant Human IL1 beta protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of Mouse D10S cells is 1 x 10^7 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag)
IL1B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (Biotin,His-Avi Tag)IL1B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1, beta (IL1B) (AA 1-269) protein (GST tag)IL1B Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) protein (Fc Tag)IL1B Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 1, beta (IL1B) (AA 170-269) protein (GST tag)IL1B Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (His tag)IL1B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (AA 118-269) (Active) protein (His tag)IL1B Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (AA 106-267) protein (His tag)IL1B Spezies: Huhn Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. When dissolved, dilute further into aqueous buffered solutions.
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Buffer
- Lyophilized from 10 mM NaC2H3O2, pH 6.5.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Andere Bezeichnung
- IL1 beta
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Hintergrund
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IL1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.
Alternative Names: IL 1 protein, EP protein, IL-1 protein, MCF protein, IL1, LAF protein, Leukocyte Endogenous Mediator protein, IL-1 beta protein, Interleukin 1 beta protein, Endogenous Pyrogen protein, IL 1, Mononuclear Cell Factor protein, Catabolin protein, Lymphocyte-activating factor protein, IL-1, LEM protein -
Molekulargewicht
- 17.3 kDa
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Pathways
- NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome
Target
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