IL12 Protein
Kurzübersicht für IL12 Protein (ABIN7884444)
Target
Alle IL12 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Verwendungszweck
- IL-12 p70 (Interleukin-12 p70), Human (mammalian cell expression)
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Sequenz
- IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STD ILKDQKEPKN KTFLRCEAKN YSGRFTCWWL TTISTDLTFS VKSSRGSSDP QGVTCGAATL SAERVRGDNK EYEYSVECQE DSACPAAEES LPIE VMVDAVHKLK YENYTSSFFI RDIIKPDPPK NLQLKPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG KSKREKKDRV FTDKTSATVI CRK NASISVRAQD RYYSSSWSEW ASVPCSGSTS GSGKPGSGEG STKGRNLPVA TPDPGMFPCL HHSQNLLRAV SNMLQKARQT LEFYPCTSEE I DHEDITKDKT STVEACLPLE LTKNESCLNS RETSFITNGS CLASRKTSFM MALCLSSIYE DLKMYQVEFK TMNAKLLMDP KRQIFLDQNM LAVI DELMQALNFN SETVPQKSSL EEPDFYKTKI KLCILLHAFR IRAVTIDRVM SYLNASHHHH HH
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Endotoxin-Niveau
- <0.1 EU per 1 μg protein
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Biological Activity Comment
- ED50 0.05-0.2 ng/mL.
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Interleukin 12 (IL12) (AA 23-328) (Active) protein (His-Avi Tag)
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (Biotin,His-Avi Tag)IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 12 (IL12) (AA 23-219), (AA 23-328) (Active) proteinIL12 Spezies: Human Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,DYKDDDDK Tag)IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,AVI tag,DYKDDDDK Tag,Biotin)IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 (IL12) proteinIL12 Spezies: Maus Wirt: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Interleukin 12 (IL12) protein (His tag)IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 12 (IL12) proteinIL12 Spezies: Human Wirt: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Interleukin 12 (IL12) (AA 23-219) protein (His tag,Fc Tag)IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag)IL12 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % SDS, AcA Active
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- dissolve in sterile H2O
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- IL12 (Interleukin 12 (IL12))
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Andere Bezeichnung
- IL-12
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Hintergrund
- Active IL-12 is a p70 disulfide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation.
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Pathways
- JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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