IL12 Protein (AA 23-215) (His tag)
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- Target Alle IL12 Proteine anzeigen
- IL12 (Interleukin 12 (IL12))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 23-215
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL12 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Mouse IL-12 Protein
- Sequenz
- Arg23-Ala215 (IL-12A) & Met23-Ser335 (IL-12B)
- Spezifität
- Uni-Prot: P43431 (IL-12A), P43432 (IL-12B)
- Produktmerkmale
- Recombinant Mouse IL-12 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg23-Ala215(IL-12A) & Met23-Ser335(IL-12B).
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product IL12 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL12 (Interleukin 12 (IL12))
- Andere Bezeichnung
- IL-12 (IL12 Produkte)
- Hintergrund
- Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
- Molekulargewicht
- 22.80 kDa(IL-12A)&35.79 kDa(IL-12B). Due to glycosylation, the protein migrates to 25-30 kDa(IL-12A)&45-55 kDa(IL-12B) based on Tris-Bis PAGE result.
- UniProt
- P43431
- Pathways
- JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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