TNFRSF1A Protein (AA 22-211) (His tag)
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- Target Alle TNFRSF1A Proteine anzeigen
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-211
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TNFRSF1A Protein ist gelabelt mit His tag.
- Sequenz
- AA 22-211
- Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
- Reinheit
- >90 % as determined by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product TNFRSF1A Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 30-211) protein (His tag)
TNFRSF1A Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 30-211) protein (Fc Tag)TNFRSF1A Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 30-211) protein (His tag)TNFRSF1A Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) protein (His-DYKDDDDK-Strep II Tag)TNFRSF1A Spezies: Human Wirt: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) proteinTNFRSF1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-212) protein (His tag)TNFRSF1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 22-211) protein (His tag)TNFRSF1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 31-130) protein (GST tag)TNFRSF1A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (AA 1-455) protein (GST tag)TNFRSF1A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) (Active) protein (His tag)TNFRSF1A Spezies: Maus Wirt: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
- Andere Bezeichnung
- TNFR1 (TNFRSF1A Produkte)
- Hintergrund
- Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).
- Molekulargewicht
- 22.3 kDa
- NCBI Accession
- NP_001056
- Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Hepatitis C, Ubiquitin Proteasome Pathway
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