IL-6 Protein (AA 25-211)
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- Target Alle IL-6 (IL6) Proteine anzeigen
- IL-6 (IL6) (Interleukin 6 (IL6))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 25-211
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Spezies
- Ratte
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Quelle
- HEK-293T Cells
- Produktmerkmale
- ED50 < 3 pg/mL, measured by a cell proliferation assay using 7TD1 Cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL6 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- IL-6 (IL6) (Interleukin 6 (IL6))
- Andere Bezeichnung
- Interleukin-6 (IL-6) (IL6 Produkte)
- Hintergrund
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Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 - Molekulargewicht
- 21-26 kDa , observed by reducing SDS-PAGE.
- UniProt
- P20607
- Pathways
- TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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