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IL-6 Protein (AA 25-211)

IL6 Spezies: Ratte Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Produktnummer ABIN2018140
  • Target Alle IL-6 (IL6) Proteine anzeigen
    IL-6 (IL6) (Interleukin 6 (IL6))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 25-211
    Spezies
    • 38
    • 21
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Quelle
    • 58
    • 24
    • 20
    • 8
    • 4
    • 4
    • 1
    • 1
    HEK-293T Cells
    Produktmerkmale
    ED50 < 3 pg/mL, measured by a cell proliferation assay using 7TD1 Cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Andere Bezeichnung
    Interleukin-6 (IL-6) (IL6 Produkte)
    Hintergrund
    Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
    Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
    Molekulargewicht
    21-26 kDa , observed by reducing SDS-PAGE.
    UniProt
    P20607
    Pathways
    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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