IL-1 beta Protein (AA 117-269)
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- Target Alle IL-1 beta (IL1B) Proteine anzeigen
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 117-269
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Spezies
- Human
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Quelle
- CHO Cells
- Produktmerkmale
- ED50< 10 pg/mL, measured in a cell proliferation assay using D10S cells, corresponding to a specific activity of >1 x 10^8 units/mg.
- Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL1B Protein
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Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag)
IL1B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag,Biotin)IL1B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Interleukin 1, beta (IL1B) (AA 1-269) protein (GST tag)IL1B Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 1, beta (IL1B) (AA 117-269) protein (Fc Tag)IL1B Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1, beta (IL1B) (AA 115-267) protein (His tag)IL1B Spezies: Schwein Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 116-268) protein (His tag)IL1B Spezies: Pferd Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 114-266) protein (His tag)IL1B Spezies: Ziege Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 115-266) protein (His tag)IL1B Spezies: Hund Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 106-267) protein (His tag)IL1B Spezies: Huhn Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 170-269) protein (GST tag)IL1B Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant human Interleukin 1 beta (IL-1 beta) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-1 beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Andere Bezeichnung
- Interleukin-1 beta (IL-1 Beta) (IL1B Produkte)
- Hintergrund
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Interleukin 1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.
Synonyms: Catabolin, Interleukin-1 beta, IL1F2 - Molekulargewicht
- 17kDa, observed by non-reducing SDS-PAGE.
- NCBI Accession
- NP_000567
- Pathways
- NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome
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