Branched Chain Amino-Acid Transaminase 1, Cytosolic Produkte
(Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
Kategorien
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010].
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Ausgewählte Branched Chain Amino-Acid Transaminase 1, Cytosolic Kategorien
Branched Chain Amino-Acid Transaminase 1, Cytosolic Antikörper
High quality antibodies with extensive validation data.
Branched Chain Amino-Acid Transaminase 1, Cytosolic Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Branched Chain Amino-Acid Transaminase 1, Cytosolic Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7445063
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7445177
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7445060
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Branched Chain Amino-Acid Transaminase 1, Cytosolic ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6227409
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Branched Chain Amino-Acid Transaminase 1, Cytosolic Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7562994
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7552661
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122027
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Branched Chain Amino-Acid Transaminase 1, Cytosolic Produkten
: "Defect of branched-chain amino acid metabolism promotes the development of Alzheimer's disease by targeting the mTOR signaling." in: Bioscience reports, Vol. 38, Issue 4, (2018) (PubMed).: "BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." in: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).
: "Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia." in: Nature, Vol. 545, Issue 7655, pp. 500-504, (2017) (PubMed).
: "Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration." in: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 327-30, (2008) (PubMed).
: "Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21528-32, (1999) (PubMed).
: "Involvement of Myc targets in c-myc and N-myc induced human tumors." in: Oncogene, Vol. 17, Issue 2, pp. 165-71, (1998) (PubMed).
: "High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8474-81, (1997) (PubMed).
: "ECA39 is regulated by c-Myc in human and by a Jun/Fos homolog, Gcn4, in yeast." in: Oncogene, Vol. 13, Issue 9, pp. 1859-66, (1997) (PubMed).
: "Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B." in: Nature, Vol. 378, Issue 6559, pp. 785-9, (1996) (PubMed).
: "Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20242-5, (1996) (PubMed).
Synonyme und alternative Namen zu Branched Chain Amino-Acid Transaminase 1, Cytosolic
branched chain amino acid transaminase 1 (BCAT1), branched chain aminotransferase 1, cytosolic (Bcat1), branched chain amino acid transaminase 1 (Bcat1), branched chain amino-acid transaminase 1, cytosolic (bcat1), branched chain amino-acid transaminase 1, cytosolic L homeolog (bcat1.L), branched chain aminotransferase 1, cytosolic (bcat1), branched chain amino acid transaminase 1 (bcat1), branched-chain amino acid transaminase 1 (BCAT-1), ATBCAT-1, BCATC, BCATc, Bcatc, BCT1, branched-chain amino acid transaminase 1, ECA39, Eca39, fj66g02, MECA39, PNAS121, PP18, T27I1.8, T27I1_8, wu:fj66g02, zgc:73157Bezeichner auf Proteinebene für Branched Chain Amino-Acid Transaminase 1, Cytosolic
- branched chain aminotransferase 1, cytosolic
- branched-chain-amino-acid aminotransferase, cytosolic
- placental protein 18
- BCAT(c)
- cytosolic branched-chain amino acid aminotransferase
- branched chain amino-acid transaminase 1, cytosolic
- branched-chain-amino-acid aminotransferase, cytosolic-like
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