Phospholipase C gamma 2 Antikörper (pTyr759) (AbBy Fluor® 488)
Kurzübersicht für Phospholipase C gamma 2 Antikörper (pTyr759) (AbBy Fluor® 488) (ABIN880131)
Target
Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr759
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr759
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Phospholipase C gamma 2 (PLCG2)
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Andere Bezeichnung
- PLC gamma 2
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Hintergrund
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Synonyms: PLC 2, PLC gamma 2, PLC IV, PLCG2, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3.1.4.11, Phosphoinositide phospholipase C, Phospholipase C gamma 2, Phospholipase C, gamma 2 phosphatidylinositol specic, PLCG2_HUMAN.
Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
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Gen-ID
- 5336
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Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Target
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