Phospholipase C gamma 2 Antikörper (AA 826-985)

Produktnummer ABIN5542312

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Target: Phospholipase C gamma 2 (PLCG2)

Bindungsspezifität: AA 826-985

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PLCG2 (AA: 826-985) expressed in E. coli.

Klon: 2D9E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu Phospholipase C gamma 2

Target: Phospholipase C gamma 2 (PLCG2)

Andere Bezeichnung: PLCG2 (PLCG2 Produkte)

Synonyme: PLCgamma2 antikoerper, Plcg-2 antikoerper, APLAID antikoerper, FCAS3 antikoerper, phospholipase C, gamma 2 antikoerper, phospholipase C gamma 2 antikoerper, phospholipase C, gamma 2 (phosphatidylinositol-specific) antikoerper, Plcg2 antikoerper, PLCG2 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.,

Aliases: FCAS3, APLAID, PLC-IV, PLC-gamma-2

Molekulargewicht: 147.9 kDa

Gen-ID: 5336

HGNC: 5336

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling