p53 Antikörper
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- Target Alle p53 (TP53) Antikörper anzeigen
- p53 (TP53) (Tumor Protein P53 (TP53))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser p53 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Positive Control: A431. Cellular Localization: Cytoplasm, nucleus
- Aufreinigung
- Immunogen affinity purified
- Isotyp
- IgG
- Top Product
- Discover our top product TP53 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5mg/ml
- Buffer
- 1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Andere Bezeichnung
- p53 (TP53 Produkte)
- Synonyme
- BCC7 antikoerper, LFS1 antikoerper, P53 antikoerper, TRP53 antikoerper, p53 antikoerper, Trp53 antikoerper, brp53 antikoerper, drp53 antikoerper, etID22686.5 antikoerper, fb40d06 antikoerper, wu:fb40d06 antikoerper, zgc:111919 antikoerper, Tp53 antikoerper, bbl antikoerper, bfy antikoerper, bhy antikoerper, p44 antikoerper, tp53 antikoerper, Xp53 antikoerper, TP53 antikoerper, tumor protein p53 antikoerper, cellular tumor antigen p53 antikoerper, transformation related protein 53 antikoerper, tumor protein p53 L homeolog antikoerper, TP53 antikoerper, CpipJ_CPIJ002758 antikoerper, Tp53 antikoerper, tp53 antikoerper, Trp53 antikoerper, tp53.L antikoerper
- Hintergrund
- P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers
- Molekulargewicht
- ~70kDa
- UniProt
- Q91XH8
- Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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