p53 Antikörper
Kurzübersicht für p53 Antikörper (ABIN866051)
Target
Alle p53 (TP53) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Positive Control: A431. Cellular Localization: Cytoplasm, nucleus
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Aufreinigung
- Immunogen affinity purified
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Isotyp
- IgG
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anti-Tumor Protein P53 (TP53) antibody
KO Validated TP53 Reaktivität: Human WB, IF, IHC (p), IP, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (N-Term) antibodyTP53 Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyTP53 Reaktivität: Human, Ratte, Maus, Affe WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 293-322) antibodyTP53 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7777 unconjugated
anti-Tumor Protein P53 (TP53) (AA 301-393) antibodyTP53 Reaktivität: Human WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 2C3 unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2C11 unconjugated
anti-Tumor Protein P53 (TP53) (full length) antibodyTP53 Reaktivität: Human, Ratte, Maus WB, IP, IHC (fro), IHC (f), ICS Wirt: Maus Monoclonal G59-12 unconjugated
anti-Tumor Protein P53 (TP53) (pSer46) antibodyTP53 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 36 unconjugated
anti-Tumor Protein P53 (TP53) (AA 378-393), (pSer392) antibodyTP53 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal FP3-2 [FPS392] unconjugated
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Applikationshinweise
- WB: 1:500-1,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5mg/ml
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Buffer
- 1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Andere Bezeichnung
- p53
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Hintergrund
- P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers
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Molekulargewicht
- ~70kDa
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UniProt
- Q91XH8
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Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
Target
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