Rekombinanter JNK Antikörper (pTyr185)

Produktnummer ABIN7938300

Der Kaninchen Monoklonal anti-JNK Antikörper (Klon 2G8) (ABIN7938300) detektiert spezifisch JNK in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Rekombinanter JNK Antikörper (pTyr185) (ABIN7938300)

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser JNK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 2G8

Produktdetails anti-JNK Antikörper

Bindungsspezifität: pTyr185

Verwendungszweck: JNK phospho Tyr185 (rAb), 100 μg (Clone 2G8)

Aufreinigung: Protein A Chromatography

Immunogen: This information is proprietary to Active Motif and/or its suppliers.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:40000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu JNK

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Andere Bezeichnung: JNK

Hintergrund: MAPK8 (Mitogen-activated protein kinase 8) is also named JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. The JNK gene generates 10 forms of JNK through alternative splicing, and the protein encoded by the JNK gene has or does not have a COOH terminal, resulting in 46 kDa and 54 kDa proteins. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun.

Molekulargewicht: 37-46 kDa

NCBI Accession: NM_139049

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine