HRAS Antikörper (AA 101-152)

Produktnummer ABIN737226

Dieses Anti-HRAS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HRAS in WB, ELISA, IF (cc), IF (p), IP, IHC (p) und IHC (fro). Geeignet für Maus und Ratte.

Kurzübersicht für HRAS Antikörper (AA 101-152) (ABIN737226)

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HRAS Antikörper

Bindungsspezifität: AA 101-152

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human H-ras

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HRAS

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Andere Bezeichnung: HRAS

Hintergrund:

Synonyms: c bas/has, c H ras, c has/bas p21 protein, C K RAS, c K ras2 protein, c Ki ras, c Kirsten ras protein, c ras Ki 2 protein, Cellular c Ki ras2 proto oncogene antibody G1III6 N ras, GTPase HRas, GTPase KRas, GTPase NRas, H Ras 1, H RasIDX, Ha Ras, HRAS 1, HRAS, HRAS1, K Ras 2, K ras, K ras p21 protein, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, Kirsten rat sarcoma 2 viral v Ki ras2 oncogene homolog, KRAS 1, KRAS 2, KRAS, KRAS1, KRAS2, N ras, N ras oncogene, Neuroblastoma RAS viral v ras oncogene homolog, NRAS 1, NRAS, NRAS1, NS3, Oncogene KRAS2, p21ras, PR310 c K ras oncogene antibody RASH 1, RASH1, RASK 2, RASK2, Transforming protein N Ras, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma viral oncogene homolog, v ras neuroblastoma RAS viral oncogene homolog, RASH_HUMAN.

Background: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq].

Gen-ID: 3265

Pathways: p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Autophagie, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling