Insulin Antikörper

Produktnummer ABIN7670774

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Insulin in ELISA (Detection). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Insulin Antikörper (ABIN7670774)

Target: Insulin (INS)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Insulin Antikörper ist unkonjugiert

Applikation: ELISA (Detection)

Klon: 9F3

Produktdetails anti-Insulin Antikörper

Verwendungszweck: Recombinant Insulin Monoclonal Antibody(Detector)

Aufreinigung: Protein A/G Purification

Immunogen: Human INS Native Protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Insulin

Target: Insulin (INS)

Andere Bezeichnung: Insulin

Hintergrund: IDDM2,ILPR,IRDN,MODY10,Insulin is a peptide hormone,produced by beta cells of the pancreas,and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization,protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule,proinsulin,which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin,while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.

UniProt: P01308

Pathways: NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation