Bcl-2 Antikörper
Kurzübersicht für Bcl-2 Antikörper (ABIN7670541)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Bcl-2 Monoclonal Antibody(Capture)
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Aufreinigung
- Protein A/G Purification
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Immunogen
- Recombinant Human Bcl-2 protein expressed by E.coli
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Isotyp
- IgG2a
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Applikationshinweise
- ELISA Capture 2-8 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Sterile PBS , pH 7.4
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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Haltbarkeit
- 12 months
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- Bcl-2
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Hintergrund
- Bcl2,PPP1R50,BCL2 belongs to the Bcl-2 family. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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UniProt
- P10415
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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