Parkin Antikörper

Produktnummer ABIN7605857

Dieses Anti-Parkin-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Parkin in WB, IHC, IF, FACS, IP und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Parkin Antikörper (ABIN7605857)

Target: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Parkin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: AOCD-16

Produktdetails anti-Parkin Antikörper

Verwendungszweck: Anti-Parkin PARK2 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-Parkin PARK2 Rabbit Monoclonal Antibody (ABIN7605857). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Parkin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu Parkin

Target: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Andere Bezeichnung: PARK2

Hintergrund:

Synonyms: E3 ubiquitin-protein ligase parkin,Parkin,6.3.2.-,Parkinson juvenile disease protein 2,Parkinson disease protein 2,PARK2,PRKN,

Tissue Specificity: Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons from kainate-mediated apoptosis. Found in serum (at protein level). .

Molekulargewicht: 36 kDa

UniProt: O60260

Pathways: Autophagie, Ubiquitin Proteasome Pathway