Bcl-2 Antikörper (N-Term)
Kurzübersicht für Bcl-2 Antikörper (N-Term) (ABIN7273031)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Anti-BCL2
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Sequenz
- MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH LTPFTARGRF ATVVEELFRD GVN
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Spezifität
- Detects a band of approximately 25 kDa by Western blot in the following cell lysate: LS174T, Jurkat and HUH.
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Kreuzreaktivität (Details)
- Reacts against human, rat, mouse, canine and monkey proteins
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Aufreinigung
- Epitope affinity purified
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Immunogen
- Recombinant affinity purified peptide derived from within residues 143 aa to the N-terminus of human BCL2 produced in E. coli.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:2,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 3 mg/mL
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Buffer
- PBS, 20 % glycerol and 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody solution should be gently mixed before use.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- BCL2
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Hintergrund
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Goat polyclonal antibody to BCL2. This protein belongs to a family that act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Regulates cell death by controlling the mitochondrial membrane permeability and appears to function in a feedback loop system with caspases.
Apoptosis Regulator Bcl-2, BCL2 Apoptosis Regulator, B-Cell CLL/Lymphoma 2, PPP1R50, Protein Phosphatase 1 Regulatory Subunit 50 antibody.
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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