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Bcl-2 Antikörper (AA 41-54)

Dieses Anti-Bcl-2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Bcl-2 in FACS. Geeignet für Human.

Produktnummer ABIN7272015

Datenblatt (PDF)

Kurzübersicht für Bcl-2 Antikörper (AA 41-54) (ABIN7272015)

Target

Alle Bcl-2 (BCL2) Antikörper anzeigen

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser Bcl-2 Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS)

Güteklasse

GMP Grade

Klon

1E2

Discover our top product BCL2 Primärantikörper

Bindungsspezifität
56

39

27

23

22

21

16

16

16

16

11

11

8

8

7

7

7

7

7

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 41-54

Verwendungszweck

BCL-2 Unconjugated Antibody

Produktmerkmale

The clone 100, a mouse monoclonal antibody, recognizes a 239 amino acid ~25 kDa human apoptosis regulator oncoprotein known as Bcl-2. It is an intracellular, integral membrane protein containing up to 4 Bcl-2 homology (BH) motifs which are found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane. Bcl-2 is a conserved anti-apoptotic protein and plays important roles in the management of normal immunity. Nonrandom translocations with breakpoint at band q21 on chromosome 18 may cause bcl-2 gene deregulation and contribute to neoplastic transformation in human lymphomas.

Aufreinigung

Purified

Reinheit

>95 %

Immunogen

Human BCL-2 synthetic peptide aa. 41-54

Isotyp

IgG1, kappa
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibody
BCL2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Huhn, Bakterien WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB04684 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reaktivität: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Wirt: Maus Monoclonal Bcl-2-100 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)
BCL2 Reaktivität: Human ICFC Wirt: Maus Monoclonal Bcl-2-100 PE

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reaktivität: Human WB, IHC, FACS, IF, StM, ISt Wirt: Maus Monoclonal 100-D5 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human WB, IHC, StM Wirt: Kaninchen Monoclonal BCL2-2210R unconjugated Recombinant Antibody

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Andere Bezeichnung

BCL-2

Gen-ID

596

UniProt

P10415

Pathways

MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling