GTPase NRas Antikörper
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- Target Alle GTPase NRas (NRAS) Antikörper anzeigen
- GTPase NRas (NRAS)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GTPase NRas Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human NRAS
- Isotyp
- IgG
- Top Product
- Discover our top product NRAS Primärantikörper
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- Applikationshinweise
- ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GTPase NRas (NRAS)
- Andere Bezeichnung
- NRAS (NRAS Produkte)
- Hintergrund
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Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Aliases: ALPS4 antibody, AV095280 antibody, GTPase NRas antibody, HRAS1 antibody, N ras antibody, N ras protein part 4 antibody, Neuroblastoma RAS viral (v ras) oncogene homolog antibody, NRAS antibody, NRAS1 antibody, NS6 antibody, OTTHUMP00000013879 antibody, OTTMUSP00000023521 antibody, RASN_HUMAN antibody, Transforming protein N Ras antibody, Transforming protein N-Ras antibody, v ras neuroblastoma RAS viral oncogene homolog antibody
- UniProt
- P01111
- Pathways
- p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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