Bcl-2 Antikörper (AA 5-205)
Kurzübersicht für Bcl-2 Antikörper (AA 5-205) (ABIN7176964)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 5-205
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Kreuzreaktivität
- Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Mouse Apoptosis regulator Bcl-2 protein (5-205AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:10-1:100,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- Bcl2
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Hintergrund
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Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Aliases: Bcl2 antibody, Bcl-2 antibody, Apoptosis regulator Bcl-2 antibody
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UniProt
- P10417
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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