Phospholipase C gamma 2 Antikörper (pTyr753)

Produktnummer ABIN7139060

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Phospholipase C gamma 2 in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Phospholipase C gamma 2 Antikörper (pTyr753) (ABIN7139060)

Target: Phospholipase C gamma 2 (PLCG2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Bindungsspezifität: pTyr753

Verwendungszweck: Phospho-PLCG2 (Tyr753) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 753 (S-L-Y(p)-D-V) derived from Human PLCg2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Phospholipase C gamma 2

Target: Phospholipase C gamma 2 (PLCG2)

Andere Bezeichnung: PLCG2

Hintergrund:

Background: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Kim YJ, et al. (2004) Mol Cell Biol 24: 9986-9999
Humphries LA, et al. (2004) J Biol Chem 279 : 37651-37661
Suzuki-Inoue K, et al. (2004) Biochem J 378 : 1023-1029
Rodriguez R, et al. (2003) Biochem J 374 : 269-280

Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase gamma-2 antibody, EC 3.1.4.11 antibody, Phosphoinositide phospholipase C antibody, Phosphoinositide phospholipase C-gamma-2 antibody, Phospholipase C gamma 2 antibody, Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody, Phospholipase C-gamma-2 antibody, Phospholipase C-IV antibody, PLC 2 antibody, PLC gamma 2 antibody, PLC IV antibody, PLC-gamma-2 antibody, PLC-IV antibody, Plcg2 antibody, PLCG2_HUMAN antibody

UniProt: P16885

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling