TRAF3 Antikörper

Produktnummer ABIN7119986

Der Kaninchen Polyklonal Anti-TRAF3-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, TRAF3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TRAF3 Antikörper (ABIN7119986)

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-TRAF3 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TNF receptor-associated factor 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200 - 1:1000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu TRAF3

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Andere Bezeichnung: TRAF3

Hintergrund: Synonyms:CAP 1, CAP1, CD40 binding protein, CD40bp, CRAF1, LAP1, LMP1 associated protein 1, TRAF3 Background:The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Molekulargewicht: 70 kDa

Gen-ID: 7187

UniProt: Q13114

Pathways: NF-kappaB Signalweg, Apoptose, TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades