TRAF3 Antikörper (C-Term)

Produktnummer ABIN657866

Der Kaninchen Polyklonal anti-TRAF3 Antikörper wird verwendet zum Nachweis von TRAF3 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für TRAF3 Antikörper (C-Term) (ABIN657866)

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB22535

Produktdetails anti-TRAF3 Antikörper

Bindungsspezifität: AA 490-517, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRAF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-517 amino acids from the C-terminal region of human TRAF3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TRAF3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu TRAF3

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Andere Bezeichnung: TRAF3

Hintergrund: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Molekulargewicht: 64490

Gen-ID: 7187

NCBI Accession: NP_001186356, NP_003291, NP_663777, NP_663778

UniProt: Q13114

Pathways: NF-kappaB Signalweg, Apoptose, TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades