Bcl-2 Antikörper (AA 1-239)
Kurzübersicht für Bcl-2 Antikörper (AA 1-239) (ABIN7111910)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-239
-
Verwendungszweck
- BCL2 antibody
-
Aufreinigung
- Protein A+G purification
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
-
Immunogen sequence: 1-239aa
Immunogen: B-cell CLL/lymphoma 2
-
Isotyp
- IgG2a
-
-
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibodyBCL2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Huhn, Bakterien WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibodyBCL2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB04684 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D1 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reaktivität: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Wirt: Maus Monoclonal Bcl-2-100 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)BCL2 Reaktivität: Human ICFC Wirt: Maus Monoclonal Bcl-2-100 PE
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reaktivität: Human WB, IHC, FACS, IF, StM, ISt Wirt: Maus Monoclonal 100-D5 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reaktivität: Human WB, IHC, StM Wirt: Kaninchen Monoclonal BCL2-2210R unconjugated Recombinant Antibody
-
-
Applikationshinweise
- WB: 1:1000-1:10000, IP: 1:500-1:5000, IHC: 1:100-1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
Andere Bezeichnung
- BCL2
-
Hintergrund
-
Synonyms: Apoptosis regulator Bcl-2|BCL2
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
-
Molekulargewicht
- 26 kDa
-
Gen-ID
- 596
-
UniProt
- P10415
-
Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
-
