MAP3K7 Antikörper (pThr187)
Kurzübersicht für MAP3K7 Antikörper (pThr187) (ABIN7250782)
Target
Alle MAP3K7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr187
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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Andere Bezeichnung
- MAP3K7
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Hintergrund
- Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
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Molekulargewicht
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Observed_MW: 60 kDa
Calculated_MW: 67 kDa
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UniProt
- O43318
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Pathways
- NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
Target
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