RIPK1 Antikörper (AA 17-289)

Produktnummer ABIN7427129

Der Maus Monoklonal anti-RIPK1 Antikörper (Klon C1) (ABIN7427129) detektiert spezifisch RIPK1 in ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RIPK1 Antikörper (AA 17-289) (ABIN7427129)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RIPK1 Antikörper ist unkonjugiert

Applikation: Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: C1

Produktdetails anti-RIPK1 Antikörper

Bindungsspezifität: AA 17-289

Verwendungszweck: Monoclonal Antibody to Receptor Interacting Serine Threonine Kinase 1 (RIPK1)

Spezifität: The antibody is a mouse monoclonal antibody raised against RIPK1. It has been selected for its ability to recognize RIPK1 in immunohistochemical staining and western blotting.

Aufreinigung: Protein A + Protein G affinity chromatography

Immunogen: Recombinant Receptor Interacting Serine Threonine Kinase 1 (RIPK1) corresdonding to Phe17~Tyr289 with N-terminal His Tag

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 5-20 μg/mL,
Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Andere Bezeichnung: RIPK1

Hintergrund: RIP, Receptor-Interacting Protein, Cell death protein RIP, Serine/threonine-protein kinase RIP

UniProt: Q13546

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Ubiquitin Proteasome Pathway