TICAM1 Antikörper (C-Term)

Produktnummer ABIN6990434

Der Kaninchen Polyklonal Anti-TICAM1-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, TICAM1 in Proben von Human zu detektieren.

Kurzübersicht für TICAM1 Antikörper (C-Term) (ABIN6990434)

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TICAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-TICAM1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: TRIF Antibody is Ion exchange chromatography purified.

Immunogen: TRIF antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF. The immunogen is located within the last 50 amino acids of TRIF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIF antibody can be used for detection of TRIF by Western blot at 1 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIF Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRIF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TICAM1

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Andere Bezeichnung: TRIF

Hintergrund: TRIF Antibody: TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κ,B.

Molekulargewicht: Predicted: 60 kDa

Observed: 55 kDa

Gen-ID: 148022

NCBI Accession: NP_891549

UniProt: Q8IUC6

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades