LRP6 Antikörper (pThr1479) (PE)

Produktnummer ABIN6988813

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch LRP6 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für LRP6 Antikörper (pThr1479) (PE) (ABIN6988813)

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP6 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-LRP6 Antikörper (PE)

Bindungsspezifität: pThr1479

Kreuzreaktivität: Human, Maus

Homologie: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Thr1479

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LRP6

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Andere Bezeichnung: LRP6

Hintergrund:

Synonyms: LRP6 Thr1479, LRP6 T1479, p-LRP6 Thr1479, p-LRP6 T1479, ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6.

Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

Gen-ID: 4040

UniProt: O75581

Pathways: WNT Signalweg, Tube Formation