PTPN11 Antikörper
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- Target Alle PTPN11 Antikörper anzeigen
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTPN11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- SHP2 between 200 to 550 amino acids
- Klon
- 8A1F
- Isotyp
- IgG
- Top Product
- Discover our top product PTPN11 Primärantikörper
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 263-329) antibody
PTPN11 Reaktivität: Human IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 6D9 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 514-593) antibodyPTPN11 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyVerified PTPN11 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyKO Validated PTPN11 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibodyPTPN11 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21493 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-460) antibodyPTPN11 Reaktivität: Human WB, PLA Wirt: Maus Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr542) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibodyPTPN11 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
- Andere Bezeichnung
- SHP2 (PTPN11 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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Synonyms: Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP-2C, SHP-2, Shp2, PTPN11, PTP2C, SHPTP2
Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
- Gen-ID
- 5781
- UniProt
- Q06124
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effekt
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