Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

Bcl-2 Antikörper (pSer70)

Name: Bcl-2 Antikörper (pSer70)
SKU: ABIN683428
Price: 384.62 EUR
Availability: InStock

BCL2 Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Mouse spleen lysates probed with Anti-Bcl-2 (Ser70) Polyclonal Antibody, Unconjugated at 1:5000 90min in 37˚C (Bcl-2 Antikörper (pSer70))

Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti Phospho-Bcl-2(Ser70) Polyclonal Antibody, Unconjugated (ABIN683428) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Bcl-2 Antikörper (pSer70))

IHC

Image submitted by OWL Validation Program. (Bcl-2 Antikörper (pSer70))

3 Abbildungen

(1 reference)

Produktnummer ABIN683428

Datenblatt (PDF)

Target Alle Bcl-2 (BCL2) Antikörper anzeigen

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
Bindungsspezifität
53

38

27

23

22

21

16

16

16

11

11

8

8

7

7

7

6

6

5

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
pSer70
Reaktivität
412

170

167

34

23

22

15

10

6

5

5

2

1

1

1

1
Human, Maus, Ratte
Wirt
322

123

5

2

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
319

135
Polyklonal
Konjugat
201

29

27

22

20

12

8

8

8

8

8

8

8

8

8

8

8

8

7

5

5

5

5

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser Bcl-2 Antikörper ist unkonjugiert
Applikation
338

184

140

109

94

93

79

65

53

30

24

23

18

8

8

8

5

4

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70

Isotyp

IgG

Top Product

Discover our top product BCL2 Primärantikörper
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibody
BCL2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibody
BCL2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Huhn, Bakterien WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB04684 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reaktivität: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Wirt: Maus Monoclonal Bcl-2-100 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)
BCL2 Reaktivität: Human FACS Wirt: Maus Monoclonal Bcl-2-100 PE

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reaktivität: Human WB, IHC, StM Wirt: Kaninchen Monoclonal BCL2-2210R unconjugated Recombinant Antibody

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Yan, Yuan, Gao, Huang, Ma, Gao, Zhang, Guo, Chen: "Overexpression of Human E46K Mutant ?-Synuclein Impairs Macroautophagy via Inactivation of JNK1-Bcl-2 Pathway." in: Molecular neurobiology, Vol. 50, Issue 2, pp. 685-701, (2014) (PubMed).
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Andere Bezeichnung

Bcl-2 (BCL2 Produkte)

Hintergrund

Synonyms: Bcl-2, Apoptosis regulator Bcl-2, Bcl2
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Gen-ID

24224

UniProt

P49950

Pathways

MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling