LRP6 Antikörper (PE)

Produktnummer ABIN681488

Der Kaninchen Polyklonal Anti-LRP6-Antikörper wurde für IF (p) validiert. Er ist geeignet, LRP6 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Schwein zu detektieren.

Kurzübersicht für LRP6 Antikörper (PE) (ABIN681488)

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP6 Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LRP6 Antikörper (PE)

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Kreuzreaktivität: Ratte (Rattus), Hund, Schwein, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human LRP6

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu LRP6

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Andere Bezeichnung: LRP6

Hintergrund: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

Molekulargewicht: 177kDa

Gen-ID: 4040

Pathways: WNT Signalweg, Tube Formation