CD14 Antikörper (AA 201-300)

Produktnummer ABIN673164

Dieses Anti-CD14-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD14 in WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc) und IF (p). Geeignet für Human, Maus, Ratte, Schaf, Hund und Kaninchen. Dieses Primary Antibody wurde in 7+ Publikationen zitiert.

Kurzübersicht für CD14 Antikörper (AA 201-300) (ABIN673164)

Target: CD14

Reaktivität: Human, Maus, Ratte, Schaf, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CD14 Antikörper

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Hund, Human, Maus, Kaninchen, Ratte, Schaf

Homologie: Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CD14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD14 Antikörper (ABIN673164)

Kulhankova, Kinney, Stach, Gourronc, Grumbach, Klingelhutz, Salgado-Pabón: "The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function." in: Infection and immunity, (2018) (PubMed).

Lee, Chen, Wallace, Sung, Sheu, Chung, Chen, Lu, Ko, Sun, Chiang, Chang, Lee, Yip: "Xenogeneic human umbilical cord-derived mesenchymal stem cells reduce mortality in rats with acute respiratory distress syndrome complicated by sepsis." in: Oncotarget, Vol. 8, Issue 28, pp. 45626-45642, (2018) (PubMed).

Sun, Chen, Chang, Chiang, Sung, Chen, Chen, Chen, Kao, Chang, Lee, Yip: "Melatonin treatment enhances therapeutic effects of exosomes against acute liver ischemia-reperfusion injury." in: American journal of translational research, Vol. 9, Issue 4, pp. 1543-1560, (2017) (PubMed).

Chang, Hsu, Yang, Sung, Chen, Huang, Kao, Chen, Chen, Chiang, Yip, Lee: "Enhanced protection against renal ischemia-reperfusion injury with combined melatonin and exendin-4 in a rodent model." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1588-602, (2017) (PubMed).

Nau, Seebach, Trumm, Schaible, Kontradowitz, Meier, Buechner, Marzi, Henrich: "Alteration of Masquelet's induced membrane characteristics by different kinds of antibiotic enriched bone cement in a critical size defect model in the rat's femur." in: Injury, Vol. 47, Issue 2, pp. 325-34, (2016) (PubMed).

Chen, Yu, Fan, Bian, Ma, Lu, Jin: "Sargassum fusiforme polysaccharide activates nuclear factor kappa-B (NF-?B) and induces cytokine production via Toll-like receptors." in: Carbohydrate polymers, Vol. 105, pp. 113-20, (2014) (PubMed).

Chen, Chiang, Chen, Sung, Lee, Tsai, Chang, Chen, Sun, Leu, Chang, Yang, Yip: "Melatonin treatment further improves adipose-derived mesenchymal stem cell therapy for acute interstitial cystitis in rat." in: Journal of pineal research, Vol. 57, Issue 3, pp. 248-61, (2014) (PubMed).

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund:

Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14

Background: In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).

Gen-ID: 12475

UniProt: P10810

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades