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TNF alpha Antikörper (C-Term)

Name: TNF alpha Antikörper (C-Term)
SKU: ABIN657455
Price: 434.77 EUR
Availability: InStock

TNF alpha Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB33595 unconjugated

TNF Antibody (C-term) (ABIN657455 and ABIN2846482) western blot analysis in HL-60 cell line lysates (35 μg/lane). (TNF alpha Antikörper (C-Term))

TNF Antibody (C-term) (ABIN657455 and ABIN2846482) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram). (TNF alpha Antikörper (C-Term))

FACS

2 Abbildungen

(1 reference)

Produktnummer ABIN657455

Datenblatt (PDF)

Target Alle TNF alpha Antikörper anzeigen

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
Bindungsspezifität
45

33

15

15

14

10

7

6

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 187-216, C-Term
Reaktivität
341

216

128

64

51

43

34

26

21

19

11

10

10

9

7

5

5

2

2

2

2

1

1

1

1
Human
Wirt
269

205

46

25

8

6

4

2

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
285

277
Polyklonal
Konjugat
272

81

45

21

17

12

6

6

6

6

6

6

6

6

6

5

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser TNF alpha Antikörper ist unkonjugiert
Applikation
353

219

139

136

74

59

53

53

47

43

42

42

37

32

20

12

11

9

9

6

6

6

6

5

5

4

4

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This TNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF.

Klon

RB33595

Isotyp

Ig Fraction

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TNF alpha Reaktivität: Human, Ratte IHC, FACS, IF, StM Wirt: Maus Monoclonal TNFA-1172 unconjugated

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TNF alpha Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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TNF alpha Reaktivität: Human, Schwein, Non-Human Primate ICFC Wirt: Maus Monoclonal MAb11 FITC

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) antibody
TNF alpha Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal M1-C4 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-227) antibody
TNF alpha Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha Reaktivität: Maus WB, IHC, IP, ICC Wirt: Maus Monoclonal C1 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 71-234) antibody
TNF alpha Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 86-150) antibody
TNF alpha Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

TNF Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit

6 months
Huang, Zhao, Yu, Yang, Ding: "Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease." in: Marine drugs, Vol. 15, Issue 2, (2017) (PubMed).
Target

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung

TNF (TNF alpha Produkte)

Hintergrund

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Molekulargewicht

25644

Gen-ID

7124

NCBI Accession

NP_000585

UniProt

P01375

Pathways

NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome