IL-1 beta Antikörper

Produktnummer ABIN641016

Der Kaninchen Polyklonal anti-IL-1 beta Antikörper (ABIN641016) detektiert spezifisch IL-1 beta in WB, ELISA und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Huhn.

Kurzübersicht für IL-1 beta Antikörper (ABIN641016)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Functional Studies (Func)

Produktdetails anti-IL-1 beta Antikörper

Verwendungszweck: Rabbit Anti-Chicken IL-1 beta

Spezifität: This product recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta. IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica. It neutralizes chicken IL-1 beta (1-2).

Produktmerkmale: Cytokines/Chemokines/Growth Factors/Receptors

Immunogen: Antisera to chicken Interleukin 1 Beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, Functional Assays, Western Blotting

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 0.5 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: Interleukin-1 beta (IL-1b)

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome