Insulin Antikörper
Kurzübersicht für Insulin Antikörper (ABIN6297596)
Target
Alle Insulin (INS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Mouse anti-Human/Mouse/Rat Insulin Antibody [Sodium Azide Free]
-
Spezifität
- Cytoplasmic
-
Aufreinigung
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
-
Immunogen
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
-
-
-
-
Applikationshinweise
-
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- In 1X PBS, BSA free, sodium azide free
-
Konservierungsmittel
- Azide free
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- Insulin (INS)
-
Andere Bezeichnung
- Insulin
-
Hintergrund
-
Target Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. [RefSeq]
Gene Symbol: INS
-
Gen-ID
- 3630
-
UniProt
- P01308
-
Pathways
- NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
-