Insulin Antikörper

Produktnummer ABIN6297596

Der Maus Monoklonal Anti-Insulin-Antikörper wurde für IHC und IF validiert. Er ist geeignet, Insulin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Insulin Antikörper (ABIN6297596)

Target: Insulin (INS)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Insulin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Insulin Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat Insulin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Recombinant INS protein was used as the immunogen for the Insulin antibody.

Immunogen: Recombinant INS protein was used as the immunogen for the Insulin antibody.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Insulin

Target: Insulin (INS)

Andere Bezeichnung: Insulin

Hintergrund:

Target Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. [RefSeq]

Gene Symbol: INS

Gen-ID: 3630

UniProt: P01308

Pathways: NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation