AKT1 Antikörper (pThr342)

Produktnummer ABIN6254017

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-AKT1 Antikörper (ABIN6254017) detektiert spezifisch AKT1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Drosophila melanogaster.

Kurzübersicht für AKT1 Antikörper (pThr342) (ABIN6254017)

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Reaktivität: Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-AKT1 Antikörper

Bindungsspezifität: pThr342

Spezifität: Specific for endogenous levels of the ~68 kDa AKT protein phosphorylated at Thr342. Immunolabeling is completely eliminated with λ-phosphatase treatment. It has been reported that this antibody may also recognize some level of phosphorylated S6K as there is 67 % homology with the sequence used as antigen.

Kreuzreaktivität: Drosophila melanogaster

Produktmerkmale: Our Anti-AKT (Thr342) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects drosophila AKT (Thr342) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Aufreinigung: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr342 of Drosophila AKT, conjugated to keyhole limpet hemocyanin (KLH)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-AKT1 Antikörper (ABIN6254017)

Woodling, Aleyakpo, Dyson, Minkley, Rajasingam, Dobson, Leung, Pomposova, Fuentealba, Alic, Partridge: "The neuronal receptor tyrosine kinase Alk is a target for longevity." in: Aging cell, Vol. 19, Issue 5, pp. e13137, (2020) (PubMed).

Post, Karashchuk, Wade, Sajid, De Meyts, Tatar: "Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity." in: Frontiers in endocrinology, Vol. 9, pp. 245, (2018) (PubMed).

Details zu AKT1

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Andere Bezeichnung: AKT1

Hintergrund:

Synonyms: AKT1 antibody, AKT1_HUMAN antibody, AKT2 antibody, AKT3 antibody, PKB alpha antibody, PKB antibody, PKB beta antibody, PKBalpha antibody, PRKBA antibody, PRKBB antibody, PRKBG antibody, Protein kinase B antibody, Protein kinase B beta antibody, Protein kinase B gamma antibody, Proto-oncogene c-Akt antibody, RAC alpha antibody, RAC antibody, RAC gamma antibody, RAC PK alpha antibody, RAC PK beta antibody, RAC PK gamma antibody, RAC-alpha serine/threonine-protein kinase antibody, RAC-PK-alpha antibody, STK2 antibody

Description Logic: Our Anti-AKT (Thr342) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects drosophila AKT (Thr342) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: AKT1

Molekulargewicht: 68 kDa

Gen-ID: 41957

UniProt: Q8INB9

Pathways: PI3K-Akt Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, AMPK Signaling, Interferon-gamma Pathway, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Water Deprivation, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGFR1 Specific Signals, VEGF Signaling, Warburg Effekt