p53 Antikörper
Kurzübersicht für p53 Antikörper (ABIN6253959)
Target
Alle p53 (TP53) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- BP53-12, produces mouse IgG2a immunoglobulins recognizes both wild and mutant forms of 53 kD protein, identified as p53 suppressor gene
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Reinheit
- PURE
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Isotyp
- IgG2a
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Applikationshinweise
- immunohistochemistry on paraffin tissue sections
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- 4 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Andere Bezeichnung
- p53
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Hintergrund
- Antigen distribution: p53 is a tumor suppressor gene encoding a nuclear phosphoprotein that plays an important role in the control of normal cell proliferation. p53 is expressed in peripheral blood and bone marrow cells of patents with some hematological malignance. p53 protein quantitation is of value to ascertain malignancy and provides additional parameter suitable for evaluation of residual disease and for the monitoring of therapy and might also be one of the methods to indicate early relapse [1]. Cellular Expression: Human carcinoma.
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Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
Target
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