p53 Antikörper (FITC)

Produktnummer ABIN610211

Der Maus Monoklonal Anti-p53-Antikörper wurde für WB, IHC und FACS validiert. Er ist geeignet, p53 in Proben von Human, Maus, Ratte, Rind (Kuh), Hamster und Huhn zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für p53 Antikörper (FITC) (ABIN610211)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hamster, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser p53 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: PAb240

Produktdetails anti-p53 Antikörper (FITC)

Spezifität: Denaturization resistant p53 epitope between amino acids 156-214. It is cross reactive with human, mouse, hamster, rat, bovine and chicken tissues.

Aufreinigung: Protein A purified

Immunogen: Murine p53 fragment expressed in E. coli.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IHC, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Product is photosensitive and should be protected from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze. Protect from light.

Referenzen für anti-p53 Antikörper (FITC) (ABIN610211)

Tomicic, Thust, Kaina: "Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation." in: Oncogene, Vol. 21, Issue 14, pp. 2141-53, (2002) (PubMed).

Jiang, Clark: "Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 6025-33, (2001) (PubMed).

Details zu p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung: TP53 / p53

Hintergrund: Name/Gene ID: TP53
Family: P53

Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

Gen-ID: 7157

UniProt: P04637

Pathways: p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt